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Cellosaurus KPC3-TRP1 (CVCL_A9ZL)

[Text version]
Cell line name KPC3-TRP1
Accession CVCL_A9ZL
Resource Identification Initiative To cite this cell line use: KPC3-TRP1 (RRID:CVCL_A9ZL)
Comments Genetic integration: Method=Transfection; Gene=MGI; MGI:98881; Tyrp1 (Note=With p.Gln512_Val537del).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Genetic integration: Method=Transgenic mouse; Gene=MGI; MGI:96680; Kras (Note=With p.Gly12Asp).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Disease Mouse pancreatic neoplasm (NCIt: C34035)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: LSL-KrasG12D:LSL-Trp53R270H:Pdx1-Cre (KPC).
Hierarchy Parent: CVCL_A9ZK (KPC3)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=30381448; DOI=10.1158/1535-7163.MCT-18-0679
Benonisson H., Altintas I., Sluijter M., Verploegen S., Labrijn A.F., Schuurhuis D.H., Houtkamp M.A., Verbeek J.S., Schuurman J., van Hall T.
CD3-bispecific antibody therapy turns solid tumors into inflammatory sites but does not install protective memory.
Mol. Cancer Ther. 18:312-322(2019)

Cross-references
Encyclopedic resources Wikidata; Q102114432
Entry history
Entry creation29-Oct-2020
Last entry update10-Sep-2024
Version number5