Cellosaurus HepG2-Lucia AhR (CVCL_A8BT)
| Cell line name | HepG2-Lucia AhR |
|---|---|
| Accession | CVCL_A8BT |
| Resource Identification Initiative | To cite this cell line use: HepG2-Lucia AhR (RRID:CVCL_A8BT) |
| Comments | Population: Caucasian. Characteristics: Used for the study of aryl hydrocarbon receptor (AhR) genomic signaling induction (InvivoGen=hpgl-ahr). Characteristics: The Lucia luciferase reporter gene is under the control of a minimal promoter coupled with the human CYP1A1 gene entire regulatory sequence which contains 6 dioxin responsive elements (DRE) (InvivoGen=hpgl-ahr). Genetic integration: Method=Transfection; Gene=UniProtKB; P17493; Streptoalloteichus hindustanus ble (BleoR). Genetic integration: Method=Transfection; Gene=Synthetic construct Lucia luciferase (Note=Synthetic gene designed on natural secreted luciferase genes from marine copepods). Derived from site: In situ; Liver; UBERON=UBERON_0002107. |
| Sequence variations |
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| Disease | Hepatoblastoma (NCIt: C3728) Hepatoblastoma (ORDO: Orphanet_449) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0027 (Hep-G2) |
| Sex of cell | Male |
| Age at sampling | 15Y |
| Category | Cancer cell line |
| Cross-references | |
| Cell line collections (Providers) | InvivoGen; hpgl-ahr |
| Cell line databases/resources | cancercelllines; CVCL_A8BT |
| Encyclopedic resources | Wikidata; Q107115335 |
| Entry history | |
| Entry creation | 20-May-2021 |
| Last entry update | 14-Aug-2025 |
| Version number | 11 |