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Cellosaurus PC-7 (CVCL_A786)

[Text version]
Cell line name PC-7
Synonyms PC 7; PC7
Accession CVCL_A786
Resource Identification Initiative To cite this cell line use: PC-7 (RRID:CVCL_A786)
Comments From: Immuno-Biological Laboratories (IBL); Tokyo; Japan.
Population: Japanese.
Derived from site: Metastatic; Lymph node; UBERON=UBERON_0000029.
Sequence variations
Disease Lung adenocarcinoma (NCIt: C3512)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_A787 (PC-7/CPT)
Sex of cell Male
Age at sampling Age unspecified
Category Cancer cell line
Publications

PubMed=758928; DOI=10.1038/bjc.1979.3; PMCID=PMC2009802
Mitsuru Kinjo, Kazunari Oka, S. Naito, Shin Kohga, Kenzo Tanaka, Shoichi Oboshi, Yoshihiro Hayata, Kosei Yasumoto;
Thromboplastic and fibrinolytic activities of cultured human cancer cell lines.
Br. J. Cancer 39:15-23(1979)

DOI=10.5795/jjscc.24.451
Masaru Tsumuraya, Takashi Nakajima, Takeo Terasaki, Tetsuro Kodama, Yukio Shimosato, Hisaaki Higuchi, Yoshio Uei;
Analysis of LDH isoenzyme patterns in cell lines of the small cell carcinoma (lung) and retinoblastoma.
Nihon Rinsho Saibo Gakkai Zasshi 24:451-456(1985)

PubMed=3731100
Nobuo Hanai, Kenya Shitara, Hajime Yoshida;
Generation of monoclonal antibodies against human lung squamous cell carcinoma and adenocarcinoma using mice rendered tolerant to normal human lung.
Cancer Res. 46:4438-4443(1986)

PubMed=2168285
Fumihiko Kanzawa, Yoshikazu Sugimoto, Koichi Minato, Kazuo Kasahara, Masami Bungo, Kazuhiko Nakagawa, Yasuhiro Fujiwara, Leroy F. Liu, Nagahiro Saijo;
Establishment of a camptothecin analogue (CPT-11)-resistant cell line of human non-small cell lung cancer: characterization and mechanism of resistance.
Cancer Res. 50:5919-5924(1990)

PubMed=1847845; DOI=10.1007/BF00685110
Yasutsuna Sasaki, Tetsu Shinkai, Kenji Eguchi, Tomohide Tamura, Yuichiro Ohe, Tohru Ohmori, Nagahiro Saijo;
Prediction of the antitumor activity of new platinum analogs based on their ex vivo pharmacodynamics as determined by bioassay.
Cancer Chemother. Pharmacol. 27:263-270(1991)

PubMed=1332703; DOI=10.1016/0006-291X(92)91094-7
Naohiro Kubota, Fumihiko Kanzawa, Kazuto Nishio, Yuichiro Takeda, Tohru Ohmori, Yasuhiro Fujiwara, Yoshiteru Terashima, Nagahiro Saijo;
Detection of topoisomerase I gene point mutation in CPT-11 resistant lung cancer cell line.
Biochem. Biophys. Res. Commun. 188:571-577(1992)

PubMed=10536175; DOI=10.3892/ijo.15.5.927
Takeshi Fujita, Masaharu Kiyama, Yoshio Tomizawa, Takashi Kohno, Jun Yokota;
Comprehensive analysis of p53 gene mutation characteristics in lung carcinoma with special reference to histological subtypes.
Int. J. Oncol. 15:927-934(1999)

PubMed=11005564; DOI=10.1038/sj.neo.7900094; PMCID=PMC1550293
Takashi Kohno, Takako Sato, Satoshi Takakura, Kimiko Takei, Kaoru Inoue, Michiho Nishioka, Jun Yokota;
Mutation and expression of the DCC gene in human lung cancer.
Neoplasia 2:300-305(2000)

PubMed=16105816; DOI=10.1158/0008-5472.CAN-05-0331
Yoshiaki Nagai, Hitoshi Miyazawa, Huqun No_last_name, Tomoaki Tanaka, Kiyoshi Udagawa, Motoyasu Kato, Shunichiro Fukuyama, Akemi Yokote, Kunihiko Kobayashi, Minoru Kanazawa, Koichi Hagiwara;
Genetic heterogeneity of the epidermal growth factor receptor in non-small cell lung cancer cell lines revealed by a rapid and sensitive detection system, the peptide nucleic acid-locked nucleic acid PCR clamp.
Cancer Res. 65:7276-7282(2005)

PubMed=19472407; DOI=10.1002/humu.21028; PMCID=PMC2900846
Raquel Blanco, Reika Iwakawa, Mo-Ying Tang, Takashi Kohno, Barbara Angulo, Ruben Pio, Luis M. Montuenga, John D. Minna, Jun Yokota, Montse Sanchez-Cespedes;
A gene-alteration profile of human lung cancer cell lines.
Hum. Mutat. 30:1199-1206(2009)

PubMed=20557307; DOI=10.1111/j.1349-7006.2010.01622.x; PMCID=PMC11158680
Reika Iwakawa, Takashi Kohno, Masatoshi Enari, Tohru Kiyono, Jun Yokota;
Prevalence of human papillomavirus 16/18/33 infection and p53 mutation in lung adenocarcinoma.
Cancer Sci. 101:1891-1896(2010)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A786
Anatomy/cell type resources BTO; BTO_0005440
Encyclopedic resources Wikidata; Q54938464
Experimental variables resources EFO; EFO_0002846
Polymorphism and mutation databases Cosmic; 801573
Cosmic; 844834
Cosmic; 876136
Cosmic; 918000
Cosmic; 946057
Cosmic; 1239895
Cosmic; 2125284
Cosmic; 2668306
IARC_TP53; 11870
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number20