Cellosaurus logo
expasy logo

Cellosaurus JW18 (CVCL_A5UW)

[Text][XML][JSON]
Cell line name JW18
Accession CVCL_A5UW
Resource Identification Initiative To cite this cell line use: JW18 (RRID:CVCL_A5UW)
Comments Group: Insect cell line.
Characteristics: Expresses a Jupiter-GFP fusion protein.
Characteristics: Constitutively infected with Wolbachia.
Doubling time: ~48 hours (PubMed=39052691).
Genetic integration: Method=Transfection/transduction; Gene=FPbase; 1XF1B; GFP (Note=avGFP; original A.victoria green fluorescent protein).
Omics: Transcriptomics; RNAseq.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Species of origin Drosophila melanogaster (Fruit fly) (NCBI Taxonomy: 7227)
Breed/subspecies: Oregon-R; FlyBase_Strain=FBsn0000276.
Hierarchy Children:
CVCL_F1ZW (JW18-wMel)CVCL_A5UX (JW18DOX)
Sex of cell Sex unspecified
Age at sampling Embryonic stage
Category Spontaneously immortalized cell line
Publications

PubMed=23028321; DOI=10.1371/journal.ppat.1002922; PMCID=PMC3447747
Laura Renee Serbus, Frederic Landmann, Walter M. Bray, Pamela M. White, Jordan Ruybal, R. Scott Lokey, Alain Debec, William Sullivan;
A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia.
PLoS Pathog. 8:e1002922.1-e1002922.12(2012)

PubMed=28159754; DOI=10.1534/genetics.116.198903; PMCID=PMC5378107
Pamela M. White, Laura Renee Serbus, Alain Debec, Adan Codina, Walter M. Bray, Antoine Guichet, R. Scott Lokey, William Sullivan;
Reliance of Wolbachia on high rates of host proteolysis revealed by a genome-wide RNAi screen of Drosophila cells.
Genetics 205:1473-1488(2017)

PubMed=30422992; DOI=10.1371/journal.ppat.1007445; PMCID=PMC6258568
Yolande Grobler, Chi Y. Yun, David J. Kahler, Casey M. Bergman, Hangnoh Lee, Brian Oliver, Ruth Lehmann;
Whole genome screen reveals a novel relationship between Wolbachia levels and Drosophila host translation.
PLoS Pathog. 14:e1007445.1-e1007445.34(2018)

PubMed=39052691; DOI=10.1371/journal.ppat.1012149; PMCID=PMC11302900
Cade Mirchandani, Pingting Wang, Jodie Jacobs, Maximilian Genetti, Evan Pepper-Tunick, William T. Sullivan, Russell Corbett-Detig, Shelbi L. Russell;
Mixed Wolbachia infections resolve rapidly during in vitro evolution.
PLoS Pathog. 20:e1012149-e1012149(2024)

Cross-references
Cell line databases/resources FlyBase_Cell_line; FBtc9000069
Encyclopedic resources Wikidata; Q107115515
Entry history
Entry creation20-May-2021
Last entry update31-Mar-2026
Version number8