ID   JW18
AC   CVCL_A5UW
DR   FlyBase_Cell_line; FBtc9000069
DR   Wikidata; Q107115515
RX   PubMed=23028321;
RX   PubMed=28159754;
RX   PubMed=30422992;
CC   Group: Insect cell line.
CC   Characteristics: Expresses a Jupiter-GFP fusion protein.
CC   Characteristics: Constitutively infected with Wolbachia.
CC   Genetic integration: Method=Transfection/transduction; Gene=FPbase; 1XF1B; GFP (Note=avGFP; original A.victoria green fluorescent protein).
CC   Omics: Transcriptomics; RNAseq.
CC   Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
OX   NCBI_TaxID=7227; ! Drosophila melanogaster (Fruit fly)
SX   Sex unspecified
AG   Embryonic stage
CA   Spontaneously immortalized cell line
DT   Created: 20-05-21; Last updated: 10-04-25; Version: 7
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RX   PubMed=23028321; DOI=10.1371/journal.ppat.1002922; PMCID=PMC3447747;
RA   Serbus L.R., Landmann F., Bray W.M., White P.M., Ruybal J.,
RA   Lokey R.S., Debec A., Sullivan W.;
RT   "A cell-based screen reveals that the albendazole metabolite,
RT   albendazole sulfone, targets Wolbachia.";
RL   PLoS Pathog. 8:e1002922.1-e1002922.12(2012).
//
RX   PubMed=28159754; DOI=10.1534/genetics.116.198903; PMCID=PMC5378107;
RA   White P.M., Serbus L.R., Debec A., Codina A., Bray W.M., Guichet A.,
RA   Lokey R.S., Sullivan W.;
RT   "Reliance of Wolbachia on high rates of host proteolysis revealed by a
RT   genome-wide RNAi screen of Drosophila cells.";
RL   Genetics 205:1473-1488(2017).
//
RX   PubMed=30422992; DOI=10.1371/journal.ppat.1007445; PMCID=PMC6258568;
RA   Grobler Y., Yun C.Y., Kahler D.J., Bergman C.M., Lee H., Oliver B.,
RA   Lehmann R.;
RT   "Whole genome screen reveals a novel relationship between Wolbachia
RT   levels and Drosophila host translation.";
RL   PLoS Pathog. 14:e1007445.1-e1007445.34(2018).
//