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Cellosaurus JW18DOX (CVCL_A5UX)

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Cell line name JW18DOX
Synonyms JW18-DOX; JW18TET
Accession CVCL_A5UX
Resource Identification Initiative To cite this cell line use: JW18DOX (RRID:CVCL_A5UX)
Comments Group: Insect cell line.
Characteristics: Expresses a Jupiter-GFP fusion protein.
Characteristics: Cured of Wolbachia infection through doxycycline treatment.
Derived from site: In situ; Whole embryo; UBERON=UBERON_0000922.
Species of origin Drosophila melanogaster (Fruit fly) (NCBI Taxonomy: 7227)
Hierarchy Parent: CVCL_A5UW (JW18)
Sex of cell Sex unspecified
Age at sampling Embryonic stage
Category Spontaneously immortalized cell line
Publications

PubMed=23028321; DOI=10.1371/journal.ppat.1002922; PMCID=PMC3447747
Laura Renee Serbus, Frederic Landmann, Walter M. Bray, Pamela M. White, Jordan Ruybal, R. Scott Lokey, Alain Debec, William Sullivan;
A cell-based screen reveals that the albendazole metabolite, albendazole sulfone, targets Wolbachia.
PLoS Pathog. 8:e1002922.1-e1002922.12(2012)

PubMed=28159754; DOI=10.1534/genetics.116.198903; PMCID=PMC5378107
Pamela M. White, Laura Renee Serbus, Alain Debec, Adan Codina, Walter M. Bray, Antoine Guichet, R. Scott Lokey, William Sullivan;
Reliance of Wolbachia on high rates of host proteolysis revealed by a genome-wide RNAi screen of Drosophila cells.
Genetics 205:1473-1488(2017)

PubMed=30422992; DOI=10.1371/journal.ppat.1007445; PMCID=PMC6258568
Yolande Grobler, Chi Y. Yun, David J. Kahler, Casey M. Bergman, Hangnoh Lee, Brian Oliver, Ruth Lehmann;
Whole genome screen reveals a novel relationship between Wolbachia levels and Drosophila host translation.
PLoS Pathog. 14:e1007445.1-e1007445.34(2018)

Cross-references
Cell line databases/resources FlyBase_Cell_line; FBtc9000070
Encyclopedic resources Wikidata; Q107115517
Entry history
Entry creation20-May-2021
Last entry update29-Jun-2023
Version number5