Cellosaurus cell line SCC-25/CP (CVCL

Cross-references
Cell line name	SCC-25/CP
Synonyms	SCC25/CP
Accession	CVCL_A5BQ
Resource Identification Initiative	To cite this cell line use: SCC-25/CP (RRID:CVCL_A5BQ)
Comments	Population: Caucasian. Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP). Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations	Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg209Lysfs*6 (c.626_627delGA); ClinVar=VCV000372539; Zygosity=Heterozygous (from parent cell line).
Disease	Tongue squamous cell carcinoma (NCIt: C4648) Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin	Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy	Parent: CVCL_1682 (SCC-25)
Sex of cell	Male
Age at sampling	70Y
Category	Cancer cell line
Publications	PubMed=3539321 Beverly A. Teicher, Sylvia A. Holden, Michael J. Kelley, Thomas C. Shea, Carol A. Cucchi, Andre Rosowsky, W. David Henner, Emil Frei 3rd; Characterization of a human squamous carcinoma cell line resistant to cis-diamminedichloroplatinum(II). Cancer Res. 47:388-393(1987) PubMed=8612713; DOI=10.1006/excr.1996.0146 Elizabeth S. Woo, Yukihiro Kondo, Simon C. Watkins, Dale G. Hoyt, John Stephen Lazo; Nucleophilic distribution of metallothionein in human tumor cells. Exp. Cell Res. 224:365-371(1996)
Anatomy/cell type resources	BTO; BTO_0006418
Encyclopedic resources	Wikidata; Q107116851
Entry history
Entry creation	20-May-2021
Last entry update	10-Apr-2025
Version number	7