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Cellosaurus SCC-25/CP (CVCL_A5BQ)

[Text version]
Cell line name SCC-25/CP
Synonyms SCC25/CP
Accession CVCL_A5BQ
Resource Identification Initiative To cite this cell line use: SCC-25/CP (RRID:CVCL_A5BQ)
Comments Population: Caucasian.
Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg209Lysfs*6 (c.626_627delGA); ClinVar=VCV000372539; Zygosity=Heterozygous (from parent cell line).
Disease Tongue squamous cell carcinoma (NCIt: C4648)
Squamous cell carcinoma of the oral tongue (ORDO: Orphanet_457252)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_1682 (SCC-25)
Sex of cell Male
Age at sampling 70Y
Category Cancer cell line
Publications

PubMed=3539321
Teicher B.A., Holden S.A., Kelley M.J., Shea T.C., Cucchi C.A., Rosowsky A., Henner W.D., Frei E. 3rd
Characterization of a human squamous carcinoma cell line resistant to cis-diamminedichloroplatinum(II).
Cancer Res. 47:388-393(1987)

PubMed=8612713; DOI=10.1006/excr.1996.0146
Woo E.S., Kondo Y., Watkins S.C., Hoyt D.G., Lazo J.S.
Nucleophilic distribution of metallothionein in human tumor cells.
Exp. Cell Res. 224:365-371(1996)

Cross-references
Anatomy/cell type resources BTO; BTO_0006418
Encyclopedic resources Wikidata; Q107116851
Entry history
Entry creation20-May-2021
Last entry update10-Apr-2025
Version number7