ID   SCC-25/CP
AC   CVCL_A5BQ
SY   SCC25/CP
DR   BTO; BTO_0006418
DR   Wikidata; Q107116851
RX   PubMed=3539321;
RX   PubMed=8612713;
CC   Population: Caucasian.
CC   Selected for resistance to: ChEBI; CHEBI_27899; Cisplatin (CDDP).
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; Simple; p.Arg209Lysfs*6 (c.626_627delGA); ClinVar=VCV000372539; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Oral cavity, tongue; UBERON=UBERON_0001723.
DI   NCIt; C4648; Tongue squamous cell carcinoma
DI   ORDO; Orphanet_457252; Squamous cell carcinoma of the oral tongue
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_1682 ! SCC-25
SX   Male
AG   70Y
CA   Cancer cell line
DT   Created: 20-05-21; Last updated: 10-04-25; Version: 7
//
RX   PubMed=3539321;
RA   Teicher B.A., Holden S.A., Kelley M.J., Shea T.C., Cucchi C.A.,
RA   Rosowsky A., Henner W.D., Frei E. 3rd;
RT   "Characterization of a human squamous carcinoma cell line resistant to
RT   cis-diamminedichloroplatinum(II).";
RL   Cancer Res. 47:388-393(1987).
//
RX   PubMed=8612713; DOI=10.1006/excr.1996.0146;
RA   Woo E.S., Kondo Y., Watkins S.C., Hoyt D.G., Lazo J.S.;
RT   "Nucleophilic distribution of metallothionein in human tumor cells.";
RL   Exp. Cell Res. 224:365-371(1996).
//