Cellosaurus logo
expasy logo

Cellosaurus PANC-1 Ecadherin EmGFP (CVCL_A4BT)

[Text version]
Cell line name PANC-1 Ecadherin EmGFP
Synonyms PANC-1 ECAD-EmGFP
Accession CVCL_A4BT
Resource Identification Initiative To cite this cell line use: PANC-1 Ecadherin EmGFP (RRID:CVCL_A4BT)
Comments Population: Caucasian.
Characteristics: Using CRISPR/Cas9 CDH1 has been tagged in one allele at the C-terminus with EmGFP. Allows to monitor the epithelial-to-mesenchymal transition (EMT) status of cells in vitro by monitoring EmGFP expression.
Transfected with: UniProtKB; P42212; GFP (with p.Ser65Thr, p.Ser72Ala, p.Asn149Lys, p.Met153Thr, p.Ile167Thr and p.His231Leu = EmGFP).
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0480 (PANC-1)
Sex of cell Male
Age at sampling 56Y
Category Cancer cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX
CSF1PO10,12
D5S81811,13
D7S8208,10
D13S31711
D16S53911
TH017,8
TPOX8,11
vWA15

Run an STR similarity search on this cell line
Cross-references
Cell line collections (Providers) ATCC; CRL-1469MET
Cell line databases/resources cancercelllines; CVCL_A4BT
Encyclopedic resources Wikidata; Q105510535
Entry history
Entry creation12-Jan-2021
Last entry update05-Oct-2023
Version number5