ID   PANC-1 Ecadherin EmGFP
AC   CVCL_A4BT
SY   PANC-1 ECAD-EmGFP
DR   ATCC; CRL-1469MET
DR   cancercelllines; CVCL_A4BT
DR   Wikidata; Q105510535
CC   Population: Caucasian.
CC   Characteristics: Using CRISPR/Cas9 CDH1 has been tagged in one allele at the C-terminus with EmGFP. Allows to monitor the epithelial-to-mesenchymal transition (EMT) status of cells in vitro by monitoring EmGFP expression.
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Heterozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 11998; TP53; Simple; p.Arg273His (c.818G>A); ClinVar=VCV000012366; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: UniProtKB; P42212; GFP (with p.Ser65Thr, p.Ser72Ala, p.Asn149Lys, p.Met153Thr, p.Ile167Thr and p.His231Leu = EmGFP).
CC   Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
ST   Source(s): ATCC
ST   Amelogenin: X
ST   CSF1PO: 10,12
ST   D13S317: 11
ST   D16S539: 11
ST   D5S818: 11,13
ST   D7S820: 8,10
ST   TH01: 7,8
ST   TPOX: 8,11
ST   vWA: 15
DI   NCIt; C9120; Pancreatic ductal adenocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0480 ! PANC-1
SX   Male
AG   56Y
CA   Cancer cell line
DT   Created: 12-01-21; Last updated: 05-10-23; Version: 5
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