Cellosaurus logo
expasy logo

Cellosaurus KBM-3 (CVCL_A425)

[Text version]
Cell line name KBM-3
Synonyms KBM3
Accession CVCL_A425
Resource Identification Initiative To cite this cell line use: KBM-3 (RRID:CVCL_A425)
Comments Doubling time: 22.9 hours (Note=At 255th passage) (PubMed=1568450).
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
Disease Adult acute myelomonocytic leukemia (NCIt: C7962)
Acute myelomonocytic leukemia (ORDO: Orphanet_517)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_IP19 (KBM-3/AMSA)CVCL_H688 (KBM-3/DOX)
Sex of cell Female
Age at sampling 32Y
Category Cancer cell line
Publications

PubMed=1995877; DOI=10.1021/jm00106a013
David Farquhar, Robert A. Newman, Joan E. Zuckerman, Borje S. Andersson;
Doxorubicin analogues incorporating chemically reactive substituents.
J. Med. Chem. 34:561-564(1991)

PubMed=1568450
Borje S. Andersson, Ulf S.R. Bergerheim, Vincent Peter Collins, Craig Childs, Miloslav Beran, Subrata Sen, Karen C. Arden, Sen Pathak, Michael Joseph Siciliano, Ake Ost, Emil J. Freireich;
KBM-3, an in vitro model of human acute myelomonocytic leukemia.
Exp. Hematol. 20:361-367(1992)

PubMed=7627932; DOI=10.1016/0165-4608(94)00282-g
Subrata Sen, Hong-Yi Zhou, Borje S. Andersson, Ann Cork, Emil J. Freireich, Sanford Alvin Stass;
p53 gene mutations with chromosome 17 abnormalities in chronic myelogenous leukemia blast crisis patients persist in long-term cell lines but may be acquired in acute myeloid leukemia cells in vitro.
Cancer Genet. Cytogenet. 82:35-40(1995)

DOI=10.1016/B978-0-12-221970-2.50457-5
Hans Gunther Drexler;
The leukemia-lymphoma cell line factsbook.
(In book) ISBN 9780122219702; pp.1-733; Academic Press; London; United Kingdom (2001)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A425
Chemistry resources ChEMBL-Cells; CHEMBL3307847
ChEMBL-Targets; CHEMBL614010
PubChem_Cell_line; CVCL_A425
Encyclopedic resources Wikidata; Q54899582
Experimental variables resources EFO; EFO_0022523
Polymorphism and mutation databases Cosmic; 975260
IARC_TP53; 4651
Entry history
Entry creation06-Jun-2012
Last entry update14-Aug-2025
Version number19