Cellosaurus logo
expasy logo

Cellosaurus HL60/MRI (CVCL_A0ST)

[Text][XML][JSON]
Cell line name HL60/MRI
Synonyms MRI
Accession CVCL_A0ST
Resource Identification Initiative To cite this cell line use: HL60/MRI (RRID:CVCL_A0ST)
Comments Population: Caucasian.
Characteristics: Cell line established from the transplantable tumor of the same name.
Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
Sequence variations
  • Gene deletion; HGNC; HGNC:11998; TP53; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
  • Mutation; HGNC; HGNC:7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
Disease Adult acute myeloid leukemia with maturation (NCIt: C7961)
Acute myeloblastic leukemia with maturation (ORDO: Orphanet_98834)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0002 (HL-60)
Sex of cell Female
Age at sampling 36Y
Category Cancer cell line
Publications

PubMed=3469018
Masue Imaizumi, Jiro Uozumi, Theodore Ronald Breitman;
Retinoic acid-induced monocytic differentiation of HL60/MRI, a cell line derived from a transplantable HL60 tumor.
Cancer Res. 47:1434-1440(1987)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A0ST
Encyclopedic resources Wikidata; Q108820479
Entry history
Entry creation23-Sep-2021
Last entry update14-Aug-2025
Version number8