ID   HL60/MRI
AC   CVCL_A0ST
SY   MRI
DR   cancercelllines; CVCL_A0ST
DR   Wikidata; Q108820479
RX   PubMed=3469018;
CC   Population: Caucasian.
CC   Characteristics: Cell line established from the transplantable tumor of the same name.
CC   Sequence variation: Gene deletion; HGNC; 11998; TP53; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 1787; CDKN2A; Simple; p.Arg80Ter (c.238C>T) (p.Pro94Leu, c.281C>T); ClinVar=VCV000009409; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Mutation; HGNC; 7989; NRAS; Simple; p.Gln61Leu (c.182A>T); ClinVar=VCV000375874; Zygosity=Heterozygous (from parent cell line).
CC   Derived from site: In situ; Peripheral blood; UBERON=UBERON_0000178.
DI   NCIt; C9154; Adult acute myeloid leukemia
DI   ORDO; Orphanet_519; Acute myeloid leukemia
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_0002 ! HL-60
SX   Female
AG   36Y
CA   Cancer cell line
DT   Created: 23-09-21; Last updated: 30-01-24; Version: 6
//
RX   PubMed=3469018;
RA   Imaizumi M., Uozumi J., Breitman T.R.;
RT   "Retinoic acid-induced monocytic differentiation of HL60/MRI, a cell
RT   line derived from a transplantable HL60 tumor.";
RL   Cancer Res. 47:1434-1440(1987).
//