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Cellosaurus IGR-CaP1 (CVCL_A018)

[Text version]
Cell line name IGR-CaP1
Synonyms Institut Gustave Roussy-Carcinoma Pancreas 1
Accession CVCL_A018
Resource Identification Initiative To cite this cell line use: IGR-CaP1 (RRID:CVCL_A018)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-4126.
Doubling time: 43 hours (PubMed=20974126).
Karyotypic information: Has lost chromosome Y.
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Sequence variations
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_WM75 (IGR-CaP1-R-caba)CVCL_IR45 (IGR-CaP1-R100)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): Patent=US8674172; PubMed=20974126

Markers:
AmelogeninX
CSF1PO11,14,16
D2S133817,24,25
D3S135814,15
D5S81812,13
D7S8209.1,10.1,11.2
D8S117913,14,15,16,17
D13S3178,10
D16S53911,12,13
D18S5114,15,16
D19S43313,14
D21S1126,30.2
FGA20,21,25,26
TH017,8,9.3
TPOX8,10,11
vWA16,20,21

Run an STR similarity search on this cell line
Publications

PubMed=20974126; DOI=10.1016/j.yexcr.2010.10.012
Anne Chauchereau, Nader Al Nakouzi, Catherine Gaudin, Sylvestre Le Moulec, Daniel Compagno, Nathalie Auger, Jean Benard, Paule Opolon, Francois Rozet, Pierre Validire, Gaelle Fromont, Karim Fizazi;
Stemness markers characterize IGR-CaP1, a new cell line derived from primary epithelial prostate cancer.
Exp. Cell Res. 317:262-275(2011)

Patent=US8674172
Anne Chauchereau, Karim Fizazi, Catherine Gaudin, Nader Al Nakouzi, Jean Benard;
Prostate cancer cell lines and their use in screening method.
Patent number US8674172, 18-Mar-2014

PubMed=24525428; DOI=10.18632/oncotarget.1574; PMCID=PMC3996665
Nader Al Nakouzi, Sophie Cotteret, Frederic Commo, Catherine Gaudin, Shanna Rajpar, Philippe Dessen, Philippe Vielh, Karim Fizazi, Anne Chauchereau;
Targeting CDC25C, PLK1 and CHEK1 to overcome docetaxel resistance induced by loss of LZTS1 in prostate cancer.
Oncotarget 5:667-678(2014)

PubMed=27198502; DOI=10.15252/emmm.201506059; PMCID=PMC4931290
Nader Al Nakouzi, Chris Ke-Dong Wang, Eliana Beraldi, Wolfgang Jager, Susan Ettinger, Ladan Fazli, Lucia Nappi, Jennifer L. Bishop, Fan Zhang, Anne Chauchereau, Yohann Loriot, Martin E. Gleave;
Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis.
EMBO Mol. Med. 8:761-778(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_A018
Encyclopedic resources Wikidata; Q54897375
Polymorphism and mutation databases IARC_TP53; 28239
Entry history
Entry creation06-Jun-2012
Last entry update19-Dec-2024
Version number16