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Cellosaurus IGR-CaP1-R100 (CVCL_IR45)

[Text version]
Cell line name IGR-CaP1-R100
Accession CVCL_IR45
Resource Identification Initiative To cite this cell line use: IGR-CaP1-R100 (RRID:CVCL_IR45)
Comments Group: Patented cell line.
Registration: International Depositary Authority, Pasteur Institute Collection Nationale de Cultures de Micro-organismes (CNCM); I-4127.
Selected for resistance to: ChEBI; CHEBI_4672; Docetaxel anhydrous (Taxotere).
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Cys (c.377A>G); ClinVar=VCV000458541; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A018 (IGR-CaP1)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
STR profile Source(s): Patent=US8674172

Markers:
AmelogeninX
CSF1PO11,12,14,15,16
D2S133817,24,25
D3S135814,15
D5S81812,13
D7S8209.1,10.1,11.2
D8S117913,14,16,17
D13S3178,10
D16S53910,11,12,13
D18S5115,16
D19S43313,14
D21S1126,30.2
FGA19,20,21,25
TH016,7,8,9.3
TPOX8,10,11
vWA16,20,21

Run an STR similarity search on this cell line
Publications

Patent=US8674172
Anne Chauchereau, Karim Fizazi, Catherine Gaudin, Nader Al Nakouzi, Jean Benard;
Prostate cancer cell lines and their use in screening method.
Patent number US8674172, 18-Mar-2014

PubMed=24525428; DOI=10.18632/oncotarget.1574; PMCID=PMC3996665
Nader Al Nakouzi, Sophie Cotteret, Frederic Commo, Catherine Gaudin, Shanna Rajpar, Philippe Dessen, Philippe Vielh, Karim Fizazi, Anne Chauchereau;
Targeting CDC25C, PLK1 and CHEK1 to overcome docetaxel resistance induced by loss of LZTS1 in prostate cancer.
Oncotarget 5:667-678(2014)

Cross-references
Cell line databases/resources cancercelllines; CVCL_IR45
Encyclopedic resources Wikidata; Q54897377
Entry history
Entry creation03-Mar-2017
Last entry update19-Dec-2024
Version number11