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Cellosaurus IGR-CaP1-R-caba (CVCL_WM75)

[Text version]
Cell line name IGR-CaP1-R-caba
Accession CVCL_WM75
Resource Identification Initiative To cite this cell line use: IGR-CaP1-R-caba (RRID:CVCL_WM75)
Comments Selected for resistance to: ChEBI; CHEBI_63584; Cabazitaxel.
Derived from site: In situ; Prostate; UBERON=UBERON_0002367.
Sequence variations
  • Mutation; HGNC; HGNC:11998; TP53; Simple; p.Tyr126Cys (c.377A>G); ClinVar=VCV000458541; Zygosity=Unspecified (from parent cell line).
Disease Prostate carcinoma (NCIt: C4863)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_A018 (IGR-CaP1)
Sex of cell Male
Age at sampling 58Y
Category Cancer cell line
Publications

PubMed=27198502; DOI=10.15252/emmm.201506059; PMCID=PMC4931290
Nader Al Nakouzi, Chris Ke-Dong Wang, Eliana Beraldi, Wolfgang Jager, Susan Ettinger, Ladan Fazli, Lucia Nappi, Jennifer L. Bishop, Fan Zhang, Anne Chauchereau, Yohann Loriot, Martin E. Gleave;
Clusterin knockdown sensitizes prostate cancer cells to taxane by modulating mitosis.
EMBO Mol. Med. 8:761-778(2016)

Cross-references
Cell line databases/resources cancercelllines; CVCL_WM75
Encyclopedic resources Wikidata; Q94314872
Entry history
Entry creation24-May-2019
Last entry update19-Dec-2024
Version number8