Cellosaurus DKO-1 (CVCL_9798)
| Cell line name | DKO-1 |
|---|---|
| Synonyms | DKO1 |
| Accession | CVCL_9798 |
| Resource Identification Initiative | To cite this cell line use: DKO-1 (RRID:CVCL_9798) |
| Comments | Population: Caucasian. Characteristics: In DLD-1 one of the two KRAS alleles has a p.Gly13Asp mutation. This cell line is KO for the normal allele. Knockout cell: Method=Homologous recombination; HGNC; HGNC:6407; KRAS (Note=1 of 2 alleles). Derived from site: In situ; Colon; UBERON=UBERON_0001155. Cell type: Epithelial cell of colon; CL=CL_0011108. |
| Disease | Colon adenocarcinoma (NCIt: C4349) |
| Species of origin | Homo sapiens (Human) (NCBI Taxonomy: 9606) |
| Hierarchy | Parent: CVCL_0248 (DLD-1) |
| Sex of cell | Male |
| Age at sampling | 67Y |
| Category | Cancer cell line |
| Publications | PubMed=8465203; DOI=10.1126/science.8465203 |
| Cross-references | |
| Cell line databases/resources | TOKU-E; 4094 |
| Encyclopedic resources | Wikidata; Q54831119 |
| Experimental variables resources | EFO; EFO_0022522 |
| Entry history | |
| Entry creation | 06-Jun-2012 |
| Last entry update | 10-Apr-2025 |
| Version number | 15 |