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Cellosaurus WA13 (CVCL_9774)

[Text version]
Cell line name WA13
Synonyms WA 13; H13; H13C; GE13; WAe004-A; WICELLe004-A; WAe013-A
Accession CVCL_9774
Resource Identification Initiative To cite this cell line use: WA13 (RRID:CVCL_9774)
Comments From: University of Wisconsin; Madison; USA.
Registration: NIH Human Embryonic Stem Cell Registry; NIHhESC-10-0063.
Registration: UK Stem Cell Bank (UKSCB); Steering comm. appl. SCSC06-18.
Omics: Genomics; Whole exome sequencing.
Omics: Transcriptomics; Microarray.
Omics: Transcriptomics; Serial analysis of gene expression (SAGE).
Omics: Variations; SNP array analysis.
Anecdotal: WA01, WA07, WA09, WA13 and WA14 were the first human embryonic stem cells to be established.
Donor information: Embryo is sibling to those giving rise to WA07 (Cellosaurus=CVCL_9772) and WA14 (Cellosaurus=CVCL_9775).
Derived from site: In situ; Blastocyst; UBERON=UBERON_0000358.
Cell type: Embryonic stem cell; CL=CL_0002322.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_C0CE (WAe013-A-1)CVCL_C0CF (WAe013-A-2)
Sex of cell Male
Age at sampling Blastocyst stage
Category Embryonic stem cell
STR profile Source(s): WiCell=wa13

Markers:
AmelogeninX,Y
CSF1PO12
D5S81811,13
D7S82010,11
D13S31711,12
D16S5399,11
TH016
TPOX8,11
vWA14,15

Run an STR similarity search on this cell line
Web pages Info; -; -; https://news.wisc.edu/nih-reapproves-wicells-h9-and-three-other-wisconsin-stem-cell-lines-for-federally-funded-research/
Info; StemCellDB; -; https://stemcelldb.nih.gov/cellLineDetails/Agilent/4
Publications

PubMed=9804556; DOI=10.1126/science.282.5391.1145
James Alexander Thomson, Joseph Itskovitz-Eldor, Sander S. Shapiro, Michelle A. Waknitz, Jennifer J. Swiergiel, Vivienne S. Marshall, Jeffrey M. Jones;
Embryonic stem cell lines derived from human blastocysts.
Science 282:1145-1147(1998)

PubMed=17570852; DOI=10.1186/gb-2007-8-6-r113; PMCID=PMC2394759
Martin Hirst, Allen Delaney, Sean A. Rogers, Angelique Schnerch, Deryck R. Persaud, Michael D. O'Connor, Thomas Zeng, Michelle Moksa, Keith Fichter, Diana Mah, Anne Go ...Show all 32 authors... , Ryan D. Morin, Agnes Baross, Yong-Jun Zhao, Jaswinder Khattra, Anna-Liisa Prabhu, Pawan Pandoh, Helen McDonald, Jennifer K. Asano, Noreen Dhalla, Kevin Ma, Stephanie Lee, Adrian Ally, Neil Chahal, Stephanie Menzies, Asim Siddiqui, Robert A. Holt, Steven J.M. Jones, Daniela S. Gerhard, James Alexander Thomson, Constance Jean Eaves, Marco Antonio Marra; Show fewer authors
LongSAGE profiling of nine human embryonic stem cell lines.
Genome Biol. 8:R113.1-R113.12(2007)

PubMed=17572666; DOI=10.1038/nbt1318
Oluseun Adewumi, Behrouz Aflatoonian, Lars Ahrlund-Richter, Michal Amit, Peter W. Andrews, Gemma Beighton, Paul A. Bello, Nissim Benvenisty, Lorraine S. Berry, Simon Bevan, Barak Blum ...Show all 85 authors... , Justin Brooking, Kevin G. Chen, Andre B.-H. Choo, Gary A. Churchill, Marie Corbel, Ivan Damjanov, Jonathan S. Draper, Petr Dvorak, Katarina Emanuelsson, Roland A. Fleck, Angela Ford, Karin Gertow, Marina Gertsenstein, Paul J. Gokhale, Rebecca S. Hamilton, Ales Hampl, Lyn E. Healy, Outi Hovatta, Johan Hyllner, Marta P. Imreh, Joseph Itskovitz-Eldor, Jamie Jackson, Jacqueline L. Johnson, Mark Jones, Kehkooi Kee, Benjamin L. King, Barbara B. Knowles, Majlinda Lako, Franck Lebrin, Barbara S. Mallon, Daisy Manning, Yoav Mayshar, Ronald Davies Graham McKay, Anna E. Michalska, Milla Mikkola, Maria Mileikovsky, Stephen Lewis Minger, Harry D. Moore, Christine L. Mummery, Andras Nagy, Norio Nakatsuji, Carmel M. O'Brien, Steve Kah-Weng Oh, Cia Olsson, Timo Otonkoski, Kye-Yoon Park, Robert Passier, Hema Patel, Minal J. Patel, Roger Arnold Pedersen, Martin F. Pera, Marian S. Piekarczyk, Renee A. Reijo Pera, Benjamin E. Reubinoff, Allan J. Robins, Janet Rossant, Peter Rugg-Gunn, Thomas C. Schulz, Henrik Semb, Eric S. Sherrer, Henrike Siemen, Glyn N. Stacey, Miodrag Stojkovic, Hirofumi Suemori, Jin Szatkiewicz, Tikva Tako Turetsky, Timo Tuuri, Stieneke van den Brink, Kristina Vintersten, Sanna Vuoristo, Dorien Ward-van Oostwaard, Thomas A. Weaver, Lesley A. Young, Wei-Dong Zhang; Show fewer authors
International Stem Cell Initiative
Characterization of human embryonic stem cell lines by the International Stem Cell Initiative.
Nat. Biotechnol. 25:803-816(2007)

PubMed=20736931; DOI=10.1038/mt.2010.179; PMCID=PMC2997587
Veronica Ramos-Mejia, Gustavo J. Melen Frajlich, Laura Sanchez, Ivan Gutierrez-Aranda, Gertrudis Ligero, Jose L. Cortes, Pedro J. Real, Clara Bueno, Pablo Menendez;
Nodal/activin signaling predicts human pluripotent stem cell lines prone to differentiate toward the hematopoietic lineage.
Mol. Ther. 18:2173-2181(2010)

PubMed=21936705; DOI=10.1089/scd.2011.0400
Veronica Ramos-Mejia, Agustin F. Fernandez, Veronica Ayllon, Pedro J. Real, Clara Bueno, Per Anderson, Francisco Martin, Mario Fernandez Fraga, Pablo Menendez;
Maintenance of human embryonic stem cells in mesenchymal stem cell-conditioned media augments hematopoietic specification.
Stem Cells Dev. 21:1549-1558(2012)

PubMed=23117585; DOI=10.1016/j.scr.2012.09.002; PMCID=PMC3590800
Barbara S. Mallon, Joshua G. Chenoweth, Kory R. Johnson, Rebecca S. Hamilton, Paul J. Tesar, Amarendra S. Yavatkar, Leonard J. Tyson, Kyeyoon Park, Kevin G. Chen, Yang-Cheng Fann, Ronald Davies Graham McKay;
StemCellDB: the human pluripotent stem cell database at the National Institutes of Health.
Stem Cell Res. 10:57-66(2013)

PubMed=28445466; DOI=10.1038/nature22312; PMCID=PMC5427175
Florian T. Merkle, Sulagna Ghosh, Nolan Kamitaki, Jana Mitchell, Yishai Avior, Curtis Mello, Seva Kashin, Shila Mekhoubad, Dusko Ilic, Maura Charlton, Genevieve Saphier ...Show all 17 authors... , Robert E. Handsaker, Giulio Genovese, Shiran Bar, Nissim Benvenisty, Steven A. McCarroll, Kevin Carl Eggan; Show fewer authors
Human pluripotent stem cells recurrently acquire and expand dominant negative p53 mutations.
Nature 545:229-233(2017)

PubMed=30388422; DOI=10.1016/j.stem.2018.10.009
Tenneille E. Ludwig, Angela Kujak, Antonio Rauti, Steven Andrzejewski, Susan Langbehn, James Mayfield, Jacqueline Fuller, Yoshimi Yashiro, Yashushi Hara, Anita Bhattacharyya;
20 years of human pluripotent stem cell research: it all started with five lines.
Cell Stem Cell 23:644-648(2018)

Cross-references
Cell line collections (Providers) WiCell; wa13
Cell line databases/resources hPSCreg; WAe013-A
NIHhESC; NIHhESC-10-0063
SKIP; SKIP001936
Biological sample resources BioSample; SAMN03471898
Encyclopedic resources Wikidata; Q54993516
Gene expression databases GEO; GSM288396
GEO; GSM347924
GEO; GSM383875
GEO; GSM384097
GEO; GSM755489
GEO; GSM755492
GEO; GSM856732
GEO; GSM862738
Entry history
Entry creation06-Jun-2012
Last entry update10-Apr-2025
Version number29