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Cellosaurus CFT-1 (CVCL_9640)

[Text version]
Cell line name CFT-1
Accession CVCL_9640
Resource Identification Initiative To cite this cell line use: CFT-1 (RRID:CVCL_9640)
Comments Population: North African.
Doubling time: 24 (PubMed=7682954).
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=pSVori-].
Derived from site: In situ; Trachea; UBERON=UBERON_0003126.
Cell type: Epithelial cell of trachea; CL=CL_0000307.
Sequence variations
  • Mutation; HGNC; 1884; CFTR; Simple; p.Ser549Asn (c.1646G>A); ClinVar=VCV000007116; Zygosity=Heterozygous (PubMed=15463957).
  • Mutation; HGNC; 1884; CFTR; Simple; p.Asn1303Lys (c.3909C>G); ClinVar=VCV000007136; Zygosity=Heterozygous (PubMed=15463957).
Disease Cystic fibrosis (NCIt: C2975)
Cystic fibrosis (ORDO: Orphanet_586)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Originate from same individual CVCL_IN79 ! CFI-3
Sex of cell Sex unspecified
Age at sampling 18FW
Category Transformed cell line
Publications

PubMed=7682954; DOI=10.1111/j.1365-2362.1993.tb00754.x
Lemnaouar M., Chastre E., Paul A., Mergey M., Veissiere D., Cherqui G., Barbry P., Simon-Bouy B., Fanen P., Gespach C., Picard J.
Oncogene-mediated propagation of tracheal epithelial cells from two cystic fibrosis fetuses with different mutations. Characterization of CFT-1 and CFT-2 cells in culture.
Eur. J. Clin. Invest. 23:151-160(1993)

PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040
Gruenert D.C., Willems M., Cassiman J.-J., Frizzell R.A.
Established cell lines used in cystic fibrosis research.
J. Cyst. Fibros. 3:191-196(2004)

Cross-references
Encyclopedic resources Wikidata; Q54811459
Entry history
Entry creation06-Jun-2012
Last entry update05-Oct-2023
Version number14