ID   CFT-1
AC   CVCL_9640
DR   Wikidata; Q54811459
RX   PubMed=7682954;
RX   PubMed=15463957;
CC   Population: North African.
CC   Doubling time: 24 (PubMed=7682954).
CC   Sequence variation: Mutation; HGNC; 1884; CFTR; Simple; p.Ser549Asn (c.1646G>A); ClinVar=VCV000007116; Zygosity=Heterozygous (PubMed=15463957).
CC   Sequence variation: Mutation; HGNC; 1884; CFTR; Simple; p.Asn1303Lys (c.3909C>G); ClinVar=VCV000007136; Zygosity=Heterozygous (PubMed=15463957).
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) [Note=pSVori-].
CC   Derived from site: In situ; Trachea; UBERON=UBERON_0003126.
CC   Cell type: Epithelial cell of trachea; CL=CL_0000307.
DI   NCIt; C2975; Cystic fibrosis
DI   ORDO; Orphanet_586; Cystic fibrosis
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
OI   CVCL_IN79 ! CFI-3
SX   Sex unspecified
AG   18FW
CA   Transformed cell line
DT   Created: 06-06-12; Last updated: 05-10-23; Version: 14
//
RX   PubMed=7682954; DOI=10.1111/j.1365-2362.1993.tb00754.x;
RA   Lemnaouar M., Chastre E., Paul A., Mergey M., Veissiere D.,
RA   Cherqui G., Barbry P., Simon-Bouy B., Fanen P., Gespach C., Picard J.;
RT   "Oncogene-mediated propagation of tracheal epithelial cells from two
RT   cystic fibrosis fetuses with different mutations. Characterization of
RT   CFT-1 and CFT-2 cells in culture.";
RL   Eur. J. Clin. Invest. 23:151-160(1993).
//
RX   PubMed=15463957; DOI=10.1016/j.jcf.2004.05.040;
RA   Gruenert D.C., Willems M., Cassiman J.-J., Frizzell R.A.;
RT   "Established cell lines used in cystic fibrosis research.";
RL   J. Cyst. Fibros. 3:191-196(2004).
//