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Cellosaurus PT45 (CVCL_8407)

[Text version]
Cell line name PT45
Synonyms PT 45; PT-45
Accession CVCL_8407
Resource Identification Initiative To cite this cell line use: PT45 (RRID:CVCL_8407)
Comments From: DiRenzo M.F.; Department of Biomedical Sciences and Human Oncology, University of Turin; Turin; Italy.
Omics: Transcriptome analysis by microarray.
Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Sequence variations
  • Mutation; HGNC; 11998; TP53; Simple; p.Arg280Lys (c.839G>A); ClinVar=VCV000376657; Zygosity=Unspecified (PubMed=1764370).
Disease Pancreatic ductal adenocarcinoma (NCIt: C9120)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_8408 (PT45-P1)
Category Cancer cell line
Publications

PubMed=1764370; DOI=10.1038/bjc.1991.467
Barton C.M., Staddon S.L., Hughes C.M., Hall P.A., O'Sullivan C., Kloppel G., Theis B., Russell R.C.G., Neoptolemos J., Williamson R.C.N., Lane D.P., Lemoine N.R.
Abnormalities of the p53 tumour suppressor gene in human pancreatic cancer.
Br. J. Cancer 64:1076-1082(1991)

PubMed=18298655; DOI=10.1111/j.1582-4934.2008.00289.x
Pilarsky C., Ammerpohl O., Sipos B., Dahl E., Hartmann A., Wellmann A., Braunschweig T., Lohr J.-M., Jesenofsky R., Friess H., Wente M.N., Kristiansen G., Jahnke B., Denz A., Ruckert F., Schackert H.K., Kloppel G., Kalthoff H., Saeger H.-D., Grutzmann R.
Activation of Wnt signalling in stroma from pancreatic cancer identified by gene expression profiling.
J. Cell. Mol. Med. 12:2823-2835(2008)

Cross-references
Cell line databases/resources cancercelllines; CVCL_8407
Chemistry resources ChEMBL-Cells; CHEMBL3307992
ChEMBL-Targets; CHEMBL612586
PubChem_Cell_line; CVCL_8407
Encyclopedic resources Wikidata; Q54948654
Polymorphism and mutation databases Cosmic; 755304
Cosmic; 808170
IARC_TP53; 946
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number17