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Cellosaurus OST (CVCL_8399)

[Text version]
Cell line name OST
Synonyms Ost; OST-1; Osteogenic Sarcoma Takase
Accession CVCL_8399
Resource Identification Initiative To cite this cell line use: OST (RRID:CVCL_8399)
Comments Problematic cell line: Contaminated. Shown to be a HeLa derivative (PubMed=20143388). Originally thought to originate from a 15 year old female patient with an osteosarcoma.
Registration: International Cell Line Authentication Committee, Register of Misidentified Cell Lines; ICLAC-00339.
Population: African American.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Derived from site: In situ; Uterus, cervix; UBERON=UBERON_0000002.
Disease Human papillomavirus-related cervical adenocarcinoma (NCIt: C27677)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_0030 (HeLa)
Sex of cell Female
Age at sampling 30Y6M
Category Cancer cell line
Web pages https://iclac.org/wp-content/uploads/Cross-Contaminations_v13_distribution.xlsx

Takebayashi S.-i.
Experimental studies on the heterologous transplantation of two kinds of cultured human osteogenic sarcoma cells into mice and rats.
Kanazawa Daigaku Juzen Igakkai Zasshi 85:135-153(1976)

PubMed=1586971; DOI=10.1247/csf.17.9
Yamada K., Yoshitake Y., Norimatsu H., Nishikawa K.
Roles of various growth factors in growth of human osteosarcoma cells which can grow in protein-free medium.
Cell Struct. Funct. 17:9-17(1992)

PubMed=12645653; DOI=10.1016/S0165-4608(02)00685-4
Ozaki T., Neumann T., Wai D.H., Schaefer K.-L., van Valen F., Lindner N., Scheel C., Boecker W., Winkelmann W., Dockhorn-Dworniczak B., Horst J., Poremba C.
Chromosomal alterations in osteosarcoma cell lines revealed by comparative genomic hybridization and multicolor karyotyping.
Cancer Genet. Cytogenet. 140:145-152(2003)

PubMed=15150091; DOI=10.1158/0008-5472.CAN-03-0809
Schaefer K.-L., Brachwitz K., Wai D.H., Braun Y., Diallo R., Korsching E., Eisenacher M., Voss R., van Valen F., Baer C., Selle B., Spahn L., Liao S.-K., Lee K.A.W., Hogendoorn P.C.W., Reifenberger G., Gabbert H.E., Poremba C.
Expression profiling of t(12;22) positive clear cell sarcoma of soft tissue cell lines reveals characteristic up-regulation of potential new marker genes including ERBB3.
Cancer Res. 64:3395-3405(2004)

PubMed=20143388; DOI=10.1002/ijc.25242
Capes-Davis A., Theodosopoulos G., Atkin I., Drexler H.G., Kohara A., MacLeod R.A.F., Masters J.R.W., Nakamura Y., Reid Y.A., Reddel R.R., Freshney R.I.
Check your cultures! A list of cross-contaminated or misidentified cell lines.
Int. J. Cancer 127:1-8(2010)

Cell line collections (Providers) RCB; RCB0454 - Discontinued
Biological sample resources BioSample; SAMN03151751
Chemistry resources ChEMBL-Cells; CHEMBL3307563
ChEMBL-Targets; CHEMBL614210
PubChem_Cell_line; CVCL_8399
Encyclopedic resources Wikidata; Q54936720
Entry history
Entry creation04-Apr-2012
Last entry update02-May-2024
Version number24