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Cellosaurus SK-ChA-1 (CVCL_6952)

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Cell line name SK-ChA-1
Synonyms SK-CHA-1; SK-ChA1; SkChA-1; SkChA1; WITT; WITT-1
Accession CVCL_6952
Resource Identification Initiative To cite this cell line use: SK-ChA-1 (RRID:CVCL_6952)
Comments Doubling time: ~48 hours (Note=At 55-60th passages) (PubMed=4056357); 26 hours (PubMed=9824643).
Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
Disease Cholangiocarcinoma (NCIt: C4436)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Female
Age at sampling 47Y
Category Cancer cell line
Publications

PubMed=4056357; DOI=10.1016/S0168-8278(85)80002-7
Alexander Knuth, Helmut Erich Gabbert, Wolfgang G. Dippold, Ortwin Klein, Walter Sachsse, Dieter Bitter-Suermann, Winfried Prellwitz, Karl-Hermann Meyer zum Buschenfelde;
Biliary adenocarcinoma. Characterisation of three new human tumor cell lines.
J. Hepatol. 1:579-596(1985)

PubMed=21533411; DOI=10.3892/ijo.10.3.545
Yoomi Moon, William K. Dahlberg, Yong-Jia Yu, Tadao Ohno, Takeshi Todoroki, John Bertram Little;
Radiosensitivity of human biliary tract cancer cell lines in vitro.
Int. J. Oncol. 10:545-551(1997)

PubMed=9824643; DOI=10.3892/ijo.13.6.1269
Naoto Koike, Takeshi Todoroki, Toru Kawamoto, Sadao Yoshida, Hironobu Kashiwagi, Katashi Fukao, Tadao Ohno, Teruo Watanabe;
The invasion potentials of human biliary tract carcinoma cell lines: correlation between invasiveness and morphologic characteristics.
Int. J. Oncol. 13:1269-1274(1998)

CLPUB00275
Sebastian Zach, Emrullah Birgin, Felix Ruckert;
Primary cholangiocellular carcinoma cell lines.
J. Stem Cell Res. Transplant. 2:1013-1013(2015)

PubMed=26486326; DOI=10.1007/s13277-015-4215-3; PMCID=PMC4844644
Giuliana Cavalloni, Caterina Peraldo-Neia, Chiara Varamo, Laura Casorzo, Carmine Dell'Aglio, Paola Bernabei, Giovanna Chiorino, Massimo Aglietta, Francesco Leone;
Establishment and characterization of a human intrahepatic cholangiocarcinoma cell line derived from an Italian patient.
Tumor Biol. 37:4041-4052(2016)

PubMed=26956050; DOI=10.18632/oncotarget.7914; PMCID=PMC4991440
Xi-Wei Ding, Roongruedee Chaiteerakij, Catherine D. Moser, Hassan M. Shaleh, Jeffrey Boakye, Gang Chen, Albert Ndzengue, Ying Li, Yan-Ling Zhou, Sheng-Bing Huang, Frank A. Sinicrope ...Show all 15 authors... , Xiao-Ping Zou, Melanie Byrne Thomas, Charles D. Smith, Lewis Rowland Roberts; Show fewer authors
Antitumor effect of the novel sphingosine kinase 2 inhibitor ABC294640 is enhanced by inhibition of autophagy and by sorafenib in human cholangiocarcinoma cells.
Oncotarget 7:20080-20092(2016)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155
Abdulkadir Isidan, Ali Yenigun, Daiki Soma, Eric Aksu, Kevin Lopez, Yujin Park, Arthur Cross-Najafi, Ping Li, Debjyoti Kundu, Michael G. House, Sanjukta Chakraborty ...Show all 17 authors... , Shannon Glaser, Lindsey Kennedy, Heather Francis, Wen-Jun Zhang, Gianfranco D. Alpini, Burcin Ekser; Show fewer authors
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references
Anatomy/cell type resources BTO; BTO_0004655
Encyclopedic resources Wikidata; Q54953627
Polymorphism and mutation databases Cosmic; 924011
Cosmic; 927191
Cosmic; 2674050
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number18