ID   SK-ChA-1
AC   CVCL_6952
SY   SK-CHA-1; SK-ChA1; SkChA-1; SkChA1; WITT; WITT-1
DR   BTO; BTO_0004655
DR   Cosmic; 924011
DR   Cosmic; 927191
DR   Cosmic; 2674050
DR   Wikidata; Q54953627
RX   CelloPub=CLPUB00275;
RX   PubMed=4056357;
RX   PubMed=9824643;
RX   PubMed=21533411;
RX   PubMed=26486326;
RX   PubMed=26956050;
RX   PubMed=35640676;
CC   Doubling time: ~48 hours (Note=At 55-60th passages) (PubMed=4056357); 26 hours (PubMed=9824643).
CC   Derived from site: Metastatic; Ascites; UBERON=UBERON_0007795.
DI   NCIt; C4436; Cholangiocarcinoma
DI   ORDO; Orphanet_70567; Cholangiocarcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
AG   47Y
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 18
//
RX   CelloPub=CLPUB00275;
RA   Zach S., Birgin E., Ruckert F.;
RT   "Primary cholangiocellular carcinoma cell lines.";
RL   J. Stem Cell Res. Transplant. 2:1013-1013(2015).
//
RX   PubMed=4056357; DOI=10.1016/S0168-8278(85)80002-7;
RA   Knuth A., Gabbert H.E., Dippold W.G., Klein O., Sachsse W.,
RA   Bitter-Suermann D., Prellwitz W., Meyer zum Buschenfelde K.-H.;
RT   "Biliary adenocarcinoma. Characterisation of three new human tumor
RT   cell lines.";
RL   J. Hepatol. 1:579-596(1985).
//
RX   PubMed=9824643; DOI=10.3892/ijo.13.6.1269;
RA   Koike N., Todoroki T., Kawamoto T., Yoshida S., Kashiwagi H.,
RA   Fukao K., Ohno T., Watanabe T.;
RT   "The invasion potentials of human biliary tract carcinoma cell lines:
RT   correlation between invasiveness and morphologic characteristics.";
RL   Int. J. Oncol. 13:1269-1274(1998).
//
RX   PubMed=21533411; DOI=10.3892/ijo.10.3.545;
RA   Moon Y., Dahlberg W.K., Yu Y.-J., Ohno T., Todoroki T., Little J.B.;
RT   "Radiosensitivity of human biliary tract cancer cell lines in vitro.";
RL   Int. J. Oncol. 10:545-551(1997).
//
RX   PubMed=26486326; DOI=10.1007/s13277-015-4215-3; PMCID=PMC4844644;
RA   Cavalloni G., Peraldo-Neia C., Varamo C., Casorzo L., Dell'Aglio C.,
RA   Bernabei P., Chiorino G., Aglietta M., Leone F.;
RT   "Establishment and characterization of a human intrahepatic
RT   cholangiocarcinoma cell line derived from an Italian patient.";
RL   Tumor Biol. 37:4041-4052(2016).
//
RX   PubMed=26956050; DOI=10.18632/oncotarget.7914; PMCID=PMC4991440;
RA   Ding X.-W., Chaiteerakij R., Moser C.D., Shaleh H.M., Boakye J.,
RA   Chen G., Ndzengue A., Li Y., Zhou Y.-L., Huang S.-B., Sinicrope F.A.,
RA   Zou X.-P., Thomas M.B., Smith C.D., Roberts L.R.;
RT   "Antitumor effect of the novel sphingosine kinase 2 inhibitor
RT   ABC294640 is enhanced by inhibition of autophagy and by sorafenib in
RT   human cholangiocarcinoma cells.";
RL   Oncotarget 7:20080-20092(2016).
//
RX   PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155;
RA   Isidan A., Yenigun A., Soma D., Aksu E., Lopez K., Park Y.,
RA   Cross-Najafi A., Li P., Kundu D., House M.G., Chakraborty S.,
RA   Glaser S., Kennedy L., Francis H., Zhang W.-J., Alpini G.D., Ekser B.;
RT   "Development and characterization of human primary cholangiocarcinoma
RT   cell lines.";
RL   Am. J. Pathol. 192:1200-1217(2022).
//