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Cellosaurus MCF10CA1h (CVCL_6683)

[Text version]

Cell line name MCF10CA1h
Accession CVCL_6683
Resource Identification Initiative To cite this cell line use: MCF10CA1h (RRID:CVCL_6683)
Comments Transfected with: HGNC; 5173; HRAS (with p.Gly12Val).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Omics: CNV analysis.
Omics: Deep proteome analysis.
Derived from sampling site: Breast; epithelium.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_WM98 (MCF10AT1k.cl2)
Sex of cell Female
Age at sampling 36Y
Category Transformed cell line
Publications

PubMed=11261825; DOI=10.1023/A:1006461422273
Santner S.J., Dawson P.J., Tait L., Soule H.D., Eliason J., Mohamed A.N., Wolman S.R., Heppner G.H., Miller F.R.
Malignant MCF10CA1 cell lines derived from premalignant human breast epithelial MCF10AT cells.
Breast Cancer Res. Treat. 65:101-110(2001)

PubMed=14523048; DOI=10.1172/JCI18899
Tang B., Vu M., Booker T., Santner S.J., Miller F.R., Anver M.R., Wakefield L.M.
TGF-beta switches from tumor suppressor to prometastatic factor in a model of breast cancer progression.
J. Clin. Invest. 112:1116-1124(2003)

PubMed=20169162; DOI=10.1371/journal.pone.0009201
Kadota M., Yang H.H., Gomez B., Sato M., Clifford R.J., Meerzaman D., Dunn B.K., Wakefield L.M., Lee M.P.
Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines.
PLoS ONE 5:E9201-E9201(2010)

PubMed=20543960; DOI=10.1371/journal.pone.0011030
Choong L.-Y., Lim S., Chong P.-K., Wong C.-Y., Shah N., Lim Y.-P.
Proteome-wide profiling of the MCF10AT breast cancer progression model.
PLoS ONE 5:E11030-E11030(2010)

Cross-references
Cell line databases/resources IGRhCellID; MCF10CA1h
Encyclopedic resources Wikidata; Q54904446
Gene expression databases GEO; GSM271344
GEO; GSM498024
GEO; GSM498028
Polymorphism and mutation databases Progenetix; CVCL_6683
Entry history
Entry creation04-Apr-2012
Last entry update22-Sep-2022
Version number18