ID   MCF10CA1h
AC   CVCL_6683
DR   cancercelllines; CVCL_6683
DR   GEO; GSM271344
DR   GEO; GSM498024
DR   GEO; GSM498028
DR   IGRhCellID; MCF10CA1h
DR   Progenetix; CVCL_6683
DR   Wikidata; Q54904446
RX   PubMed=11261825;
RX   PubMed=14523048;
RX   PubMed=20169162;
RX   PubMed=20543960;
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 5173; HRAS (with p.Gly12Val).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Omics: CNV analysis.
CC   Omics: Deep proteome analysis.
CC   Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008359.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_WM98 ! MCF10AT1k.cl2
SX   Female
AG   36Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 21
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RX   PubMed=11261825; DOI=10.1023/A:1006461422273;
RA   Santner S.J., Dawson P.J., Tait L., Soule H.D., Eliason J.F.,
RA   Mohamed A.N., Wolman S.R., Heppner G.H., Miller F.R.;
RT   "Malignant MCF10CA1 cell lines derived from premalignant human breast
RT   epithelial MCF10AT cells.";
RL   Breast Cancer Res. Treat. 65:101-110(2001).
//
RX   PubMed=14523048; DOI=10.1172/JCI18899;
RA   Tang B.-W., Vu M., Booker T., Santner S.J., Miller F.R., Anver M.R.,
RA   Wakefield L.M.;
RT   "TGF-beta switches from tumor suppressor to prometastatic factor in a
RT   model of breast cancer progression.";
RL   J. Clin. Invest. 112:1116-1124(2003).
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RX   PubMed=20169162; DOI=10.1371/journal.pone.0009201;
RA   Kadota M., Yang H.H., Gomez B.P., Sato M., Clifford R.J., Meerzaman D.,
RA   Dunn B.K., Wakefield L.M., Lee M.P.;
RT   "Delineating genetic alterations for tumor progression in the MCF10A
RT   series of breast cancer cell lines.";
RL   PLoS ONE 5:E9201-E9201(2010).
//
RX   PubMed=20543960; DOI=10.1371/journal.pone.0011030;
RA   Choong L.-Y., Lim S., Chong P.-K., Wong C.-Y., Shah N., Lim Y.-P.;
RT   "Proteome-wide profiling of the MCF10AT breast cancer progression
RT   model.";
RL   PLoS ONE 5:E11030-E11030(2010).
//