Cellosaurus logo
expasy logo

Cellosaurus MCF10CA1a (CVCL_6675)

[Text version]
Cell line name MCF10CA1a
Accession CVCL_6675
Resource Identification Initiative To cite this cell line use: MCF10CA1a (RRID:CVCL_6675)
Comments Transfected with: HGNC; 5173; HRAS (with p.Gly12Val).
Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
Omics: CNV analysis.
Omics: Glycoproteome analysis by proteomics.
Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008359.
Sequence variations
  • Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
  • Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_WM98 (MCF10AT1k.cl2)
CVCL_6676 (MCF10CA1a.cl1)
Sex of cell Female
Age at sampling 36Y
Category Transformed cell line

PubMed=11261825; DOI=10.1023/A:1006461422273
Santner S.J., Dawson P.J., Tait L., Soule H.D., Eliason J., Mohamed A.N., Wolman S.R., Heppner G.H., Miller F.R.
Malignant MCF10CA1 cell lines derived from premalignant human breast epithelial MCF10AT cells.
Breast Cancer Res. Treat. 65:101-110(2001)

PubMed=15375546; DOI=10.3892/ijo.25.4.961
Peng X., Yun D., Christov K.
Breast cancer progression in MCF10A series of cell lines is associated with alterations in retinoic acid and retinoid X receptors and with differential response to retinoids.
Int. J. Oncol. 25:961-971(2004)

PubMed=20169162; DOI=10.1371/journal.pone.0009201
Kadota M., Yang H.H., Gomez B., Sato M., Clifford R.J., Meerzaman D., Dunn B.K., Wakefield L.M., Lee M.P.
Delineating genetic alterations for tumor progression in the MCF10A series of breast cancer cell lines.
PLoS ONE 5:E9201-E9201(2010)

PubMed=24262153; DOI=10.1016/j.jprot.2013.11.006
Yen T.-Y., Haste N., Timpe L.C., Litsakos-Cheung C., Yen R., Macher B.A.
Using a cell line breast cancer progression system to identify biomarker candidates.
J. Proteomics 96:173-183(2014)

Cell line databases/resources cancercelllines; CVCL_6675
Encyclopedic resources Wikidata; Q54904434
Gene expression databases GEO; GSM498025
GEO; GSM498029
Polymorphism and mutation databases Progenetix; CVCL_6675
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number22