ID   MCF10CA1a
AC   CVCL_6675
DR   cancercelllines; CVCL_6675
DR   GEO; GSM498025
DR   GEO; GSM498029
DR   IGRhCellID; MCF10CA1a
DR   Progenetix; CVCL_6675
DR   Wikidata; Q54904434
RX   PubMed=11261825;
RX   PubMed=15375546;
RX   PubMed=20169162;
RX   PubMed=24262153;
CC   Sequence variation: Gene deletion; HGNC; 1787; CDKN2A; Zygosity=Homozygous (from parent cell line).
CC   Sequence variation: Gene deletion; HGNC; 1788; CDKN2B; Zygosity=Homozygous (from parent cell line).
CC   Transfected with: HGNC; 5173; HRAS (with p.Gly12Val).
CC   Transfected with: UniProtKB; P00552; Transposon Tn5 neo.
CC   Omics: CNV analysis.
CC   Omics: Glycoproteome analysis by proteomics.
CC   Derived from site: In situ; Breast, epithelium; UBERON=UBERON_0008359.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_WM98 ! MCF10AT1k.cl2
SX   Female
AG   36Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 05-10-23; Version: 22
RX   PubMed=11261825; DOI=10.1023/A:1006461422273;
RA   Santner S.J., Dawson P.J., Tait L., Soule H.D., Eliason J.F.,
RA   Mohamed A.N., Wolman S.R., Heppner G.H., Miller F.R.;
RT   "Malignant MCF10CA1 cell lines derived from premalignant human breast
RT   epithelial MCF10AT cells.";
RL   Breast Cancer Res. Treat. 65:101-110(2001).
RX   PubMed=15375546; DOI=10.3892/ijo.25.4.961;
RA   Peng X.-Y., Yun D.-R., Christov K.;
RT   "Breast cancer progression in MCF10A series of cell lines is
RT   associated with alterations in retinoic acid and retinoid X receptors
RT   and with differential response to retinoids.";
RL   Int. J. Oncol. 25:961-971(2004).
RX   PubMed=20169162; DOI=10.1371/journal.pone.0009201;
RA   Kadota M., Yang H.H., Gomez B.P., Sato M., Clifford R.J., Meerzaman D.,
RA   Dunn B.K., Wakefield L.M., Lee M.P.;
RT   "Delineating genetic alterations for tumor progression in the MCF10A
RT   series of breast cancer cell lines.";
RL   PLoS ONE 5:E9201-E9201(2010).
RX   PubMed=24262153; DOI=10.1016/j.jprot.2013.11.006;
RA   Yen T.-Y., Haste N., Timpe L.C., Litsakos-Cheung C., Yen R.,
RA   Macher B.A.;
RT   "Using a cell line breast cancer progression system to identify
RT   biomarker candidates.";
RL   J. Proteomics 96:173-183(2014).