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Cellosaurus GT1 (CVCL_6235)

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Cell line name GT1
Synonyms GT-1
Accession CVCL_6235
Resource Identification Initiative To cite this cell line use: GT1 (RRID:CVCL_6235)
Comments Genetic integration: Method=Transgenic mouse; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40).
Derived from site: In situ; Brain, hypothalamus; UBERON=UBERON_0001898.
Cell type: GnRH neuron; CL=CL_0011111.
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: (C57BL/6J x BALB/cJ) F2 transgenic with rat Gnrh1 promoter-Tg(SV40).
Hierarchy Children:
CVCL_6236 (GT1-1)CVCL_6237 (GT1-3)CVCL_0281 (GT1-7)
Category Transformed cell line
Publications

PubMed=2196069; DOI=10.1016/0896-6273(90)90028-E
Pamela L. Mellon, Jolene J. Windle, Paul C. Goldsmith, Cheryl A. Padula, James L. Roberts, Richard I. Weiner;
Immortalization of hypothalamic GnRH neurons by genetically targeted tumorigenesis.
Neuron 5:1-10(1990)

PubMed=18406727; DOI=10.1016/1043-2760(95)00228-6
Margaret E. Wierman, Zhao-Qin Fang, Jadwiga K. Kepa;
GnRH gene expression in neuronal cell lines.
Trends Endocrinol. Metab. 7:60-65(1996)

Cross-references
Anatomy/cell type resources BTO; BTO_0003898
Encyclopedic resources Wikidata; Q54871825
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number14