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Cellosaurus ICR B20 (CVCL_5G40)

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Cell line name ICR B20
Synonyms B20
Accession CVCL_5G40
Resource Identification Initiative To cite this cell line use: ICR B20 (RRID:CVCL_5G40)
Comments Group: Amphibian cell line.
Group: Haploid karyotype cell line.
Selected for resistance to: ChEBI; CHEBI_472552; 5-bromo-2'-deoxyuridine (Bromodeoxyuridine; BrdU; BUdR).
Transformant: ChEBI; CHEBI_189531; Benzo(b)(1,5)naphthyridine,7-chloro-10-(3-(N-(2-chloroethyl)-N-ethyl)aminopropylamino)-2-methoxy-,dihydrochloride (ICR 340).
Species of origin Lithobates pipiens (Northern leopard frog) (Rana pipiens) (NCBI Taxonomy: 8404)
Hierarchy Parent: CVCL_4345 (ICR-2A)
Sex of cell Sex unspecified
Age at sampling Embryo
Category Spontaneously immortalized cell line
Publications

DOI=10.2172/4607053
Jerome J. Freed;
Cellular heredity in haploid cultures of somatic cells. Progress Report, December 1971-November 1972.
(In technical document) Office of Scientific and Technical Information, Technical report COO-3110-8; pp.1-18; U.S. Department of Energy; Oak Ridge; USA (1972)

DOI=10.2172/4623769
Liselotte Mezger-Freed;
Effect of mutagens on BUdR resistance in haploid cells: genetic or epigenetic.
(In technical document) Office of Scientific and Technical Information, Technical report COO-3110-7/CONF-721055-1; pp.1-23; U.S. Department of Energy; Oak Ridge; USA (1972)

PubMed=4543150; DOI=10.1002/jcp.1040820208
Jerome J. Freed, Liselotte Mezger-Freed;
Origin of thymidine kinase deficient (TK-) haploid frog cells via an intermediate thymidine transport deficient (TT-) phenotype.
J. Cell. Physiol. 82:199-212(1973)

PubMed=1261610; DOI=10.1016/0014-4827(76)90687-X
Jerome J. Freed, Irene M. Hames;
Loss of a termolabile thymidine kinase activity in bromodioxyuridine resistant (transport deficient, kinase positive) haploid cultured frog cells.
Exp. Cell Res. 99:126-134(1976)

Cross-references
Encyclopedic resources Wikidata; Q54897233
Entry history
Entry creation14-Dec-2015
Last entry update19-Dec-2024
Version number9