ID   ICR B20
AC   CVCL_5G40
SY   B20
DR   Wikidata; Q54897233
RX   DOI=10.2172/4607053;
RX   DOI=10.2172/4623769;
RX   PubMed=1261610;
RX   PubMed=4543150;
CC   Group: Amphibian cell line.
CC   Group: Haploid karyotype cell line.
CC   Selected for resistance to: ChEBI; CHEBI:472552; 5-bromo-2'-deoxyuridine (Bromodeoxyuridine; BrdU; BUdR).
CC   Transformant: ChEBI; CHEBI:189531; Benzo(b)(1,5)naphthyridine,7-chloro-10-(3-(N-(2-chloroethyl)-N-ethyl)aminopropylamino)-2-methoxy-,dihydrochloride (ICR 340).
OX   NCBI_TaxID=8404; ! Lithobates pipiens (Northern leopard frog)
HI   CVCL_4345 ! ICR-2A
SX   Sex unspecified
AG   Embryo
CA   Spontaneously immortalized cell line
DT   Created: 14-12-15; Last updated: 21-03-23; Version: 8
//
RX   DOI=10.2172/4607053;
RA   Freed J.J.;
RT   "Cellular heredity in haploid cultures of somatic cells. Progress
RT   Report, December 1971-November 1972.";
RL   (In) Office of Scientific and Technical Information, Technical report COO-3110-8; pp.1-18; U.S. Department of Energy; Oak Ridge (1972).
//
RX   DOI=10.2172/4623769;
RA   Mezger-Freed L.;
RT   "Effect of mutagens on BUdR resistance in haploid cells: genetic or
RT   epigenetic.";
RL   (In) Office of Scientific and Technical Information, Technical report COO-3110-7/CONF-721055-1; pp.1-23; U.S. Department of Energy; Oak Ridge (1972).
//
RX   PubMed=1261610; DOI=10.1016/0014-4827(76)90687-X;
RA   Freed J.J., Hames I.M.;
RT   "Loss of a termolabile thymidine kinase activity in bromodioxyuridine
RT   resistant (transport deficient, kinase positive) haploid cultured frog
RT   cells.";
RL   Exp. Cell Res. 99:126-134(1976).
//
RX   PubMed=4543150; DOI=10.1002/jcp.1040820208;
RA   Freed J.J., Mezger-Freed L.;
RT   "Origin of thymidine kinase deficient (TK-) haploid frog cells via an
RT   intermediate thymidine transport deficient (TT-) phenotype.";
RL   J. Cell. Physiol. 82:199-212(1973).
//