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Cellosaurus CHO-DXB11 F435 (CVCL_5A31)

[Text version]
Cell line name CHO-DXB11 F435
Synonyms F435
Accession CVCL_5A31
Resource Identification Initiative To cite this cell line use: CHO-DXB11 F435 (RRID:CVCL_5A31)
Comments Genetic integration: Method=Transfection; Gene=HGNC; HGNC:3546; F8 (Note=Construct called N8 with 20-769 and 1657-2351).
Genetic integration: Method=Transfection; Gene=MGI; MGI:94890; Dhfr.
Transformant: ChEBI; CHEBI_23994; Ethyl methanesulfonate (Methylsulfonic acid ethyl ester; MSEE).
Transformant: NCIt; C44386; Gamma radiation.
Omics: Genomics; Whole genome sequencing.
Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Gene deletion; UniProtKB; Q2MH30; Dhfr; Zygosity=Heterozygous (from parent cell line).
  • Mutation; UniProtKB; Q2MH30; Dhfr; Simple; p.Thr137Arg (c.410G>C); Zygosity=Heterozygous (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_1977 (CHO-DXB11)
Sex of cell Female
Age at sampling Adult
Category Transformed cell line
Publications

PubMed=19906157; DOI=10.1111/j.1365-2516.2009.02135.x
Lars Thim, Brian Stidsen Vandahl, Johan Karlsson, Niels Kristian Klausen, J. Pedersen, Thomas Nylandsted Krogh, Marianne Kjalke, Jorn Meidahl Petersen, Laust Bruun Johnsen, Gert Bolt, Peder L. Norby, Thomas Dock Steenstrup;
Purification and characterization of a new recombinant factor VIII (N8).
Haemophilia 16:349-359(2010)

PubMed=25887056; DOI=10.1186/s12864-015-1391-x; PMCID=PMC4359788
Christian Schroder Kaas, Claus Kristensen, Michael J. Betenbaugh, Mikael Rordam Andersen;
Sequencing the CHO DXB11 genome reveals regional variations in genomic stability and haploidy.
BMC Genomics 16:160.1-160.9(2015)

Cross-references
Encyclopedic resources Wikidata; Q54833139
Entry history
Entry creation14-Dec-2015
Last entry update10-Apr-2025
Version number11