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Cellosaurus VACO 235 (CVCL_5175)

[Text version]
Cell line name VACO 235
Synonyms VACO235; VACO-235; V235
Accession CVCL_5175
Resource Identification Initiative To cite this cell line use: VACO 235 (RRID:CVCL_5175)
Comments Derived from site: In situ; Colon; UBERON=UBERON_0001155.
Sequence variations
Disease Colon carcinoma (NCIt: C4910)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_5176 (VACO 411)
Sex of cell Female
Category Cancer cell line
Publications

PubMed=3567899
James K.V. Willson, Gerard N. Bittner, Terry DeWayne Oberley, Lorraine Faxon Meisner, James L. Weese;
Cell culture of human colon adenomas and carcinomas.
Cancer Res. 47:2704-2713(1987)

PubMed=2253215
Suzanne J. Baker, Antonette C. Preisinger, John Milburn Jessup, Christos Paraskeva, Sanford David Markowitz, James K.V. Willson, Stanley R. Hamilton, Bert Vogelstein;
p53 gene mutations occur in combination with 17p allelic deletions as late events in colorectal tumorigenesis.
Cancer Res. 50:7717-7722(1990)

PubMed=8132740; DOI=10.1172/JCI117048; PMCID=PMC294021
Sanford David Markowitz, Lois Lemmermann Myeroff, Mark J. Cooper, June L. Traicoff, Mary E. Kochera, James D. Lutterbaugh, Margaret Swiriduk, James K.V. Willson;
A benign cultured colon adenoma bears three genetically altered colon cancer oncogenes, but progresses to tumorigenicity and transforming growth factor-beta independence without inactivating the p53 tumor suppressor gene.
J. Clin. Invest. 93:1005-1013(1994)

Cross-references
Cell line databases/resources ColonAtlas; VACO235
Encyclopedic resources Wikidata; Q54992697
Polymorphism and mutation databases Cosmic; 736333
Cosmic; 956085
IARC_TP53; 23619
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number14