ID   VACO 235
AC   CVCL_5175
SY   VACO235; VACO-235; V235
DR   ColonAtlas; VACO235
DR   Cosmic; 736333
DR   Cosmic; 956085
DR   IARC_TP53; 23619
DR   Wikidata; Q54992697
RX   PubMed=2253215;
RX   PubMed=3567899;
RX   PubMed=8132740;
CC   Sequence variation: Mutation; HGNC; HGNC:11998; TP53; None_reported; -; Zygosity=- (PubMed=2253215).
CC   Derived from site: In situ; Colon; UBERON=UBERON_0001155.
DI   NCIt; C4910; Colon carcinoma
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Female
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 14
//
RX   PubMed=2253215;
RA   Baker S.J., Preisinger A.C., Jessup J.M., Paraskeva C., Markowitz S.D.,
RA   Willson J.K.V., Hamilton S.R., Vogelstein B.;
RT   "p53 gene mutations occur in combination with 17p allelic deletions as
RT   late events in colorectal tumorigenesis.";
RL   Cancer Res. 50:7717-7722(1990).
//
RX   PubMed=3567899;
RA   Willson J.K.V., Bittner G.N., Oberley T.D., Meisner L.F., Weese J.L.;
RT   "Cell culture of human colon adenomas and carcinomas.";
RL   Cancer Res. 47:2704-2713(1987).
//
RX   PubMed=8132740; DOI=10.1172/JCI117048; PMCID=PMC294021;
RA   Markowitz S.D., Myeroff L.L., Cooper M.J., Traicoff J.L., Kochera M.E.,
RA   Lutterbaugh J.D., Swiriduk M., Willson J.K.V.;
RT   "A benign cultured colon adenoma bears three genetically altered colon
RT   cancer oncogenes, but progresses to tumorigenicity and transforming
RT   growth factor-beta independence without inactivating the p53 tumor
RT   suppressor gene.";
RL   J. Clin. Invest. 93:1005-1013(1994).
//