Cellosaurus cell line MT-CHC01 (CVCL

Cellosaurus MT-CHC01 (CVCL_4Z41)

[Text version]

Cell line name

MT-CHC01

Accession

CVCL_4Z41

Resource Identification Initiative

To cite this cell line use: MT-CHC01 (RRID:CVCL_4Z41)

Comments

Population: Caucasian; Italian.
Characteristics: Established from a mouse xenograft (PubMed=26486326).
Doubling time: ~40 hours (PubMed=26486326); 25.3 hours (PubMed=30979003).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.

Sequence variations

Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (PubMed=26486326).

Disease

Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)

Species of origin

Homo sapiens (Human) (NCBI Taxonomy: 9606)

Hierarchy

Children:

CVCL_C1L3 (MT-CHC01R1.5)

Sex of cell

Female

Age at sampling

60Y

Category

Cancer cell line

Publications

PubMed=26486326; DOI=10.1007/s13277-015-4215-3; PMCID=PMC4844644
Giuliana Cavalloni, Caterina Peraldo-Neia, Chiara Varamo, Laura Casorzo, Carmine Dell'Aglio, Paola Bernabei, Giovanna Chiorino, Massimo Aglietta, Francesco Leone;
Establishment and characterization of a human intrahepatic cholangiocarcinoma cell line derived from an Italian patient.
Tumor Biol. 37:4041-4052(2016)

PubMed=30979003; DOI=10.3390/cancers11040519; PMCID=PMC6520787
Chiara Varamo, Caterina Peraldo-Neia, Paola Ostano, Marco Basirico, Chiara Raggi, Paola Bernabei, Tiziana Venesio, Enrico Berrino, Massimo Aglietta, Francesco Leone, Giuliana Cavalloni;
Establishment and characterization of a new intrahepatic cholangiocarcinoma cell line resistant to gemcitabine.
Cancers (Basel) 11:519.1-519.22(2019)

PubMed=35640676; DOI=10.1016/j.ajpath.2022.05.007; PMCID=PMC9472155
Abdulkadir Isidan, Ali Yenigun, Daiki Soma, Eric Aksu, Kevin Lopez, Yujin Park, Arthur Cross-Najafi, Ping Li, Debjyoti Kundu, Michael G. House, Sanjukta Chakraborty ...Show all 17 authors... , Shannon Glaser, Lindsey Kennedy, Heather Francis, Wen-Jun Zhang, Gianfranco D. Alpini, Burcin Ekser; Show fewer authors
Development and characterization of human primary cholangiocarcinoma cell lines.
Am. J. Pathol. 192:1200-1217(2022)

Cross-references

Cell line databases/resources

cancercelllines; CVCL_4Z41

Encyclopedic resources

Wikidata; Q54906955

Gene expression databases

GEO; GSM3209135
GEO; GSM3209136

Entry history

Entry creation

14-Dec-2015

Last entry update

10-Apr-2025

Version number