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Cellosaurus MT-CHC01R1.5 (CVCL_C1L3)

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Cell line name MT-CHC01R1.5
Accession CVCL_C1L3
Resource Identification Initiative To cite this cell line use: MT-CHC01R1.5 (RRID:CVCL_C1L3)
Comments Population: Caucasian; Italian.
Doubling time: 49.1 hours (PubMed=30979003).
Selected for resistance to: ChEBI; CHEBI_175901; Gemcitabine (Gemzar).
Omics: Transcriptomics; Microarray.
Derived from site: In situ; Liver; UBERON=UBERON_0002107.
Sequence variations
  • Mutation; HGNC; HGNC:6407; KRAS; Simple; p.Gly12Asp (c.35G>A); ClinVar=VCV000012582; Zygosity=Unspecified (from parent cell line).
Disease Intrahepatic cholangiocarcinoma (NCIt: C35417)
Cholangiocarcinoma (ORDO: Orphanet_70567)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4Z41 (MT-CHC01)
Sex of cell Female
Age at sampling 60Y
Category Cancer cell line
Publications

PubMed=30979003; DOI=10.3390/cancers11040519; PMCID=PMC6520787
Chiara Varamo, Caterina Peraldo-Neia, Paola Ostano, Marco Basirico, Chiara Raggi, Paola Bernabei, Tiziana Venesio, Enrico Berrino, Massimo Aglietta, Francesco Leone, Giuliana Cavalloni;
Establishment and characterization of a new intrahepatic cholangiocarcinoma cell line resistant to gemcitabine.
Cancers (Basel) 11:519.1-519.22(2019)

Cross-references
Cell line databases/resources cancercelllines; CVCL_C1L3
Encyclopedic resources Wikidata; Q114312328
Gene expression databases GEO; GSM3209137
GEO; GSM3209138
Entry history
Entry creation22-Sep-2022
Last entry update10-Apr-2025
Version number7