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Cellosaurus pRNS-1-1 (CVCL_4890)

[Text version]
Cell line name pRNS-1-1
Accession CVCL_4890
Resource Identification Initiative To cite this cell line use: pRNS-1-1 (RRID:CVCL_4890)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRNS-1).
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_4891 (pRNS-1-1/ras)CVCL_4899 (SCID 5045-4)
Sex of cell Male
Age at sampling 53Y
Category Transformed cell line
Publications

PubMed=21566988; DOI=10.3892/ijo.4.4.821
Lee M.-S., Garkovenko E., Yun J.S., Weijerman P.C., Peehl D.M., Chen L.-S., Rhim J.S.
Characterization of adult human prostatic epithelial-cells immortalized by polybrene-induced DNA transfection with a plasmid containing an origin-defective SV40-genome.
Int. J. Oncol. 4:821-830(1994)

PubMed=8977636; DOI=10.1002/(SICI)1097-0045(199612)29:6<386::AID-PROS7>3.0.CO;2-6
Webber M.M., Bello D., Quader S.T.A.
Immortalized and tumorigenic adult human prostatic epithelial cell lines: characteristics and applications. Part I. Cell markers and immortalized nontumorigenic cell lines.
Prostate 29:386-394(1996)

PubMed=21544329; DOI=10.3892/ijo.8.1.41
Gross C., Skowronski R.J., Plymate S.R., Rhim J.S., Peehl D.M., Feldman D.
Simian virus 40-, but not human papillomavirus-, transformation of prostatic epithelial cells results in loss of growth-inhibition by 1,25-dihydroxyvitamin D-3.
Int. J. Oncol. 8:41-47(1996)

PubMed=9276642; DOI=10.1093/carcin/18.8.1643
Peehl D.M., Wong S.T., Sellers R.G., Jin S., Rhim J.S.
Loss of response to epidermal growth factor and retinoic acid accompanies the transformation of human prostatic epithelial cells to tumorigenicity with v-Ki-ras.
Carcinogenesis 18:1643-1650(1997)

Cross-references
Encyclopedic resources Wikidata; Q54948366
Entry history
Entry creation04-Apr-2012
Last entry update10-Sep-2024
Version number13