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Cellosaurus pRNS-1-1/ras (CVCL_4891)

[Text version]
Cell line name pRNS-1-1/ras
Accession CVCL_4891
Resource Identification Initiative To cite this cell line use: pRNS-1-1/ras (RRID:CVCL_4891)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P01117; Kirsten murine sarcoma virus k-Ras (v-Ki-ras).
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRNS-1).
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4890 (pRNS-1-1)
Sex of cell Male
Age at sampling 53Y
Category Transformed cell line
Web pages Info; CaP CLDb; -; https://web.archive.org/web/20160321225449/http://capcelllines.ca/details.asp?id=173
Publications

PubMed=9276642; DOI=10.1093/carcin/18.8.1643
Peehl D.M., Wong S.T., Sellers R.G., Jin S., Rhim J.S.
Loss of response to epidermal growth factor and retinoic acid accompanies the transformation of human prostatic epithelial cells to tumorigenicity with v-Ki-ras.
Carcinogenesis 18:1643-1650(1997)

Cross-references
Encyclopedic resources Wikidata; Q54948367
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number13