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Cellosaurus pRNS-1-1/ras (CVCL_4891)

[Text version]
Cell line name pRNS-1-1/ras
Accession CVCL_4891
Resource Identification Initiative To cite this cell line use: pRNS-1-1/ras (RRID:CVCL_4891)
Comments Genetic integration: Method=Transfection; Gene=UniProtKB; P01117; Kirsten murine sarcoma virus k-Ras (v-Ki-ras).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; Simian virus 40 (SV40) large T antigen.
Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRNS-1).
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_4890 (pRNS-1-1)
Sex of cell Male
Age at sampling 53Y
Category Transformed cell line
Web pages Info; CaP CLDb; -; https://web.archive.org/web/20160321225449/http://capcelllines.ca/details.asp?id=173
Publications

PubMed=9276642; DOI=10.1093/carcin/18.8.1643
Donna M. Peehl, Stephen T. Wong, Robert G. Sellers, Sun-Ji Jin, Johng Sik Rhim;
Loss of response to epidermal growth factor and retinoic acid accompanies the transformation of human prostatic epithelial cells to tumorigenicity with v-Ki-ras.
Carcinogenesis 18:1643-1650(1997)

Cross-references
Encyclopedic resources Wikidata; Q54948367
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number14