ID   pRNS-1-1
AC   CVCL_4890
DR   Wikidata; Q54948366
RX   PubMed=8977636;
RX   PubMed=9276642;
RX   PubMed=21544329;
RX   PubMed=21566988;
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P03070; SV40 large T antigen.
CC   Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Transposon Tn5 neo.
CC   Transformant: NCBI_TaxID; 1891767; Simian virus 40 (SV40) (Note=pRNS-1).
CC   Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
CC   Cell type: Epithelial cell of prostate; CL=CL_0002231.
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
SX   Male
AG   53Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-09-24; Version: 13
//
RX   PubMed=8977636; DOI=10.1002/(SICI)1097-0045(199612)29:6<386::AID-PROS7>3.0.CO;2-6;
RA   Webber M.M., Bello D., Quader S.T.A.;
RT   "Immortalized and tumorigenic adult human prostatic epithelial cell
RT   lines: characteristics and applications. Part I. Cell markers and
RT   immortalized nontumorigenic cell lines.";
RL   Prostate 29:386-394(1996).
//
RX   PubMed=9276642; DOI=10.1093/carcin/18.8.1643;
RA   Peehl D.M., Wong S.T., Sellers R.G., Jin S., Rhim J.S.;
RT   "Loss of response to epidermal growth factor and retinoic acid
RT   accompanies the transformation of human prostatic epithelial cells to
RT   tumorigenicity with v-Ki-ras.";
RL   Carcinogenesis 18:1643-1650(1997).
//
RX   PubMed=21544329; DOI=10.3892/ijo.8.1.41;
RA   Gross C., Skowronski R.J., Plymate S.R., Rhim J.S., Peehl D.M.,
RA   Feldman D.;
RT   "Simian virus 40-, but not human papillomavirus-, transformation of
RT   prostatic epithelial cells results in loss of growth-inhibition by
RT   1,25-dihydroxyvitamin D-3.";
RL   Int. J. Oncol. 8:41-47(1996).
//
RX   PubMed=21566988; DOI=10.3892/ijo.4.4.821;
RA   Lee M.-S., Garkovenko E., Yun J.S., Weijerman P.C., Peehl D.M.,
RA   Chen L.-S., Rhim J.S.;
RT   "Characterization of adult human prostatic epithelial-cells
RT   immortalized by polybrene-induced DNA transfection with a plasmid
RT   containing an origin-defective SV40-genome.";
RL   Int. J. Oncol. 4:821-830(1994).
//