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Cellosaurus LL/2 (LLC1) (CVCL_4358)

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Cell line name LL/2 (LLC1)
Synonyms LL/2 (LLc1); LL/2(LLc1); LL/2; LL2; LLC1; LLC; Lewis lung carcinoma line 1; Lewis lung carcinoma; Lewis Lung Cancer; Lewis-Lung; Lewis Lung
Accession CVCL_4358
Resource Identification Initiative To cite this cell line use: LL/2 (LLC1) (RRID:CVCL_4358)
Comments Doubling time: 21 hours (CLS).
Omics: HLA class I peptidome analysis by proteomics.
Omics: Transcriptome analysis.
Caution: Could be identical to 3LL (CVCL_5653).
Derived from sampling site: Lung.
Disease Malignant tumors of the mouse pulmonary system (NCIt: C21769)
Species of origin Mus musculus (Mouse) (NCBI Taxonomy: 10090)
Breed/subspecies: C57BL/6.
Hierarchy Children:
CVCL_RA22 (LL/2-eGFP-Puro )CVCL_RA23 (LL/2-Fluc-Neo/eGFP-Puro )CVCL_RA24 (LL/2-Fluc-Puro )
CVCL_RA25 (LL/2-iRFP-Puro )CVCL_5J40 (LL/2-luc-M38 )CVCL_A4CM (LL/2-Luc2 )
CVCL_RA26 (LL/2-mNIS (monoclonal) )CVCL_RA27 (LL/2-mNIS-Neo/eGFP-Puro )CVCL_RA28 (LL/2-mNIS-Neo/Fluc-Puro )
CVCL_RA29 (LL/2-mNIS-Puro )CVCL_5J02 (LL/2-Red-FLuc )CVCL_H949 (LLAK )
Category Cancer cell line
STR profile Source(s): PubMed=31220119

Mouse STR 1-115,17,18
Mouse STR 1-218,19,20
Mouse STR 2-115,16
Mouse STR 3-213,14
Mouse STR 4-220.3,21.3,23.3
Mouse STR 5-516,17,18
Mouse STR 6-417,18
Mouse STR 6-714,15,16
Mouse STR 7-126.2,27.2,28.2
Mouse STR 8-116
Mouse STR 11-213.3,14.3,15.3,16
Mouse STR 12-117
Mouse STR 13-117,18
Mouse STR 15-322.3,24.3
Mouse STR 17-214,15,16
Mouse STR 18-315,16
Mouse STR 19-213
Mouse STR X-124,26,28

Run an STR similarity search on this cell line
Web pages https://www.thermofisher.com/ch/en/home/technical-resources/cell-lines/l/cell-lines-detail-352.html

PubMed=7226139; DOI=10.1016/0304-3835(80)90130-5
Bertram J.S., Janik P.
Establishment of a cloned line of Lewis lung carcinoma cells adapted to cell culture.
Cancer Lett. 11:63-73(1980)

Yoshino K., Saijo K., Noro C., Nakamura Y.
Development of a simple method to determine the mouse strain from which cultured cell lines originated.
Interdisciplinary Bio Central 2:1-9(2010)

PubMed=28599420; DOI=10.3892/ol.2017.5877
Stankevicius V., Kuodyte K., Schveigert D., Bulotiene D., Paulauskas T., Daniunaite K., Suziedelis K.
Gene and miRNA expression profiles of mouse Lewis lung carcinoma LLC1 cells following single or fractionated dose irradiation.
Oncol. Lett. 13:4190-4200(2017)

PubMed=30084848; DOI=10.1038/sdata.2018.157
Schuster H., Shao W.-G., Weiss T., Pedrioli P.G.A., Roth P., Weller M., Campbell D.S., Deutsch E.W., Moritz R.L., Planz O., Rammensee H.-G., Aebersold R., Caron E.
A tissue-based draft map of the murine MHC class I immunopeptidome.
Sci. Data 5:180157-180157(2018)

PubMed=31220119; DOI=10.1371/journal.pone.0218412
Almeida J.L., Dakic A., Kindig K., Kone M., Letham D.L.D., Langdon S., Peat R., Holding-Pillai J., Hall E.M., Ladd M., Shaffer M.D., Berg H., Li J.-L., Wigger G., Lund S., Steffen C.R., Fransway B.B., Geraghty B., Natoli M., Bauer B., Gollin S.M., Lewis D.W., Reid Y.A.
Interlaboratory study to validate a STR profiling method for intraspecies identification of mouse cell lines.
PLoS ONE 14:E0218412-E0218412(2019)

Cell line collections AddexBio; C0016030/5000
ATCC; CRL-1642
BCRC; 60050
BCRJ; 0145
CLS; 400263
ECACC; 90020104
KCB; KCB 200781YJ
NCBI_Iran; C587
RCB; RCB0558
TKG; TKG 0153
Cell line databases/resources CLO; CLO_0007325
CLO; CLO_0050167
CLDB; cl3208
CCRID; 1101MOU-PUMC000673
TOKU-E; 2205
Anatomy/cell type resources BTO; BTO:0000181
Biological sample resources BioSample; SAMN11397632
Chemistry resources ChEMBL-Cells; CHEMBL3307859
ChEMBL-Targets; CHEMBL614088
Encyclopedic resources Wikidata; Q54902678
Gene expression databases GEO; GSE84108
Proteomic databases PRIDE; PXD008733
Entry history
Entry creation04-Apr-2012
Last entry update23-Jun-2022
Version number28