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Cellosaurus PaCa-3 (CVCL_4011)

[Text version]
Cell line name PaCa-3
Synonyms MIA PaCa-3; Mia-Paca 3; Paca-3; PaCa3; PACA3; PC-3; PC 3; PC3; Pc3
Accession CVCL_4011
Resource Identification Initiative To cite this cell line use: PaCa-3 (RRID:CVCL_4011)
Comments Derived from site: In situ; Pancreas; UBERON=UBERON_0001264.
Disease Pancreatic carcinoma (NCIt: C207229)
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Sex of cell Male
Category Cancer cell line
Web pages Info; Pawefish; -; https://www.cellosaurus.org/pawefish/PancCellLineDescriptions/PaCa-3.html
Publications

CLPUB00718
Manon von Bulow, T. Scharfe, Gunter Kloppel, Horst Franz Kern;
Establishment and characterization of continuous tumor-cell lines from human pancreatic carcinoma in vitro.
Digestion 25:17-18(1982)

PubMed=8194712; DOI=10.1016/0016-5085(94)90422-7
Babette Simon, Rolf Weinel, Martin Hohne, Jutta Watz, Jorg Schmidt, Gunther Kortner, Rudolf Arnold;
Frequent alterations of the tumor suppressor genes p53 and DCC in human pancreatic carcinoma.
Gastroenterology 106:1645-1651(1994)

PubMed=11169959; DOI=10.1002/1097-0215(200002)9999:9999<::AID-IJC1049>3.0.CO;2-C
Vorapan Sirivatanauksorn, Yongyut Sirivatanauksorn, Patricia A. Gorman, Jeffrey M. Davidson, Denise Sheer, Patrick S. Moore, Aldo Scarpa, Paul A.W. Edwards, Nicholas Robert Lemoine;
Non-random chromosomal rearrangements in pancreatic cancer cell lines identified by spectral karyotyping.
Int. J. Cancer 91:350-358(2001)

PubMed=11787853; DOI=10.1007/s004280100474
Patrick S. Moore, Bence Sipos, Simonetta Orlandini, Claudio Sorio, Francisco X. Real, Nicholas Robert Lemoine, Thomas M. Gress, Claudio Bassi, Gunter Kloppel, Holger Kalthoff, Hendrik Ungefroren ...Show all 13 authors... , Johannes-Matthias Lohr, Aldo Scarpa; Show fewer authors
Genetic profile of 22 pancreatic carcinoma cell lines. Analysis of K-ras, p53, p16 and DPC4/Smad4.
Virchows Arch. 439:798-802(2001)

PubMed=12800145; DOI=10.1002/gcc.10218
Jose Adelaide, Huai-En Huang, Anne Murati, Amber E. Alsop, Beatrice Orsetti, Marie-Joelle Mozziconacci, Cornel Popovici, Christophe Ginestier, Anne Letessier, Celine Basset, Celine Courtay-Cahen ...Show all 16 authors... , Jocelyne Jacquemier, Charles Theillet, Daniel Birnbaum, Paul A.W. Edwards, Max Chaffanet; Show fewer authors
A recurrent chromosome translocation breakpoint in breast and pancreatic cancer cell lines targets the neuregulin/NRG1 gene.
Genes Chromosomes Cancer 37:333-345(2003)

Cross-references
Encyclopedic resources Wikidata; Q54905681
Polymorphism and mutation databases Cosmic; 710862
Cosmic; 1108336
Cosmic; 1320460
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number16