Cellosaurus cell line RT4-D6P2T (CVCL

Cellosaurus RT4-D6P2T (CVCL_4006)

[Text version]

Cell line name

RT4-D6P2T

Synonyms

RT4-D6-P2T; D6P2T

Accession

CVCL_4006

Resource Identification Initiative

To cite this cell line use: RT4-D6P2T (RRID:CVCL_4006)

Comments

Transformant: ChEBI; CHEBI_23995; N-ethyl-N-nitrosourea (ENU).
Derived from site: In situ; Peripheral nervous system, sciatic nerve; UBERON=UBERON_0001322.
Cell type: Schwann cell; CL=CL_0002573.

Disease

Rat malignant schwannoma (NCIt: C60465)

Species of origin

Rattus norvegicus (Rat) (NCBI Taxonomy: 10116)
Breed/subspecies: BDIX; RS=RS_0000091.

Hierarchy

Parent: CVCL_6E50 (RT4-D6)
Children:

CVCL_D3XZ (RT4 NF2.17 #6)	CVCL_D3Y0 (RT4 NF2.17 #8)	CVCL_D3Y1 (RT4 NF2.E106G #27)
CVCL_D3Y2 (RT4 NF2.K413E #4)	CVCL_D3Y3 (RT4 NF2.K413E #8)	CVCL_D3Y5 (RT4 NF2.L64P #10)
CVCL_D3Y4 (RT4 NF2.L64P #7)	CVCL_D3Y6 (RT4 NF2.Q538P #8)	CVCL_D3XY (RT4-54)
CVCL_JK04 (RT4-67)

Category

Cancer cell line

Publications

PubMed=2824698; DOI=10.1111/j.1471-4159.1987.tb02453.x
Rashmi Bansal, Steven E. Pfeiffer;
Regulated galactolipid synthesis and cell surface expression in Schwann cell line D6P2T.
J. Neurochem. 49:1902-1911(1987)

PubMed=11316791; DOI=10.1101/gad.189601; PMCID=PMC312675
Helen Morrison, Larry S. Sherman, James Legg, Fatima Banine, Clare Isacke, Carrie Ann Haipek, David Hillel Gutmann, Helmut Ponta, Peter Herrlich;
The NF2 tumor suppressor gene product, merlin, mediates contact inhibition of growth through interactions with CD44.
Genes Dev. 15:968-980(2001)

PubMed=12210843; DOI=10.1002/jnr.10327
Mehreen Hai, Naser Muja, George H. de Vries, Richard Hudson Quarles, Pragna I. Patel;
Comparative analysis of Schwann cell lines as model systems for myelin gene transcription studies.
J. Neurosci. Res. 69:497-508(2002)

Cross-references

Cell line collections (Providers)

ATCC; CRL-2768
BCRC; 60508
BCRJ; 0399
ECACC; 93011415

Cell line databases/resources

CLO; CLO_0008893
CLDB; cl4200

Anatomy/cell type resources

BTO; BTO_0001205

Encyclopedic resources

Wikidata; Q54951363

Experimental variables resources

EFO; EFO_0022778

Proteomic databases