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Cellosaurus RWPE-2 (CVCL_3792)

[Text version]
Cell line name RWPE-2
Synonyms RWPE2
Accession CVCL_3792
Resource Identification Initiative To cite this cell line use: RWPE-2 (RRID:CVCL_3792)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11610.
Population: Caucasian.
Transfected with: UniProtKB; P01117; Kirsten murine sarcoma virus Ki-Ras.
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: SNP array analysis.
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3791 (RWPE-1)
Children:
CVCL_3793 (RWPE2-W99)
Sex of cell Male
Age at sampling 54Y
Category Transformed cell line
STR profile Source(s): ATCC

Markers:
AmelogeninX,Y
CSF1PO13
D5S81812,15
D7S82010,11
D13S3178,14
D16S5399,11
TH018,9.3
TPOX8,11
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=9018337; DOI=10.1002/(SICI)1097-0045(19970101)30:1<58::AID-PROS9>3.0.CO;2-H
Webber M.M., Bello D., Quader S.T.A.
Immortalized and tumorigenic adult human prostatic epithelial cell lines: characteristics and applications Part 2. Tumorigenic cell lines.
Prostate 30:58-64(1997)

PubMed=9214605; DOI=10.1093/carcin/18.6.1215
Bello D., Webber M.M., Kleinman H.K., Wartinger D.D., Rhim J.S.
Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18.
Carcinogenesis 18:1215-1223(1997)

PubMed=9214606; DOI=10.1093/carcin/18.6.1225
Webber M.M., Bello D., Kleinman H.K., Hoffman M.P.
Acinar differentiation by non-malignant immortalized human prostatic epithelial cells and its loss by malignant cells.
Carcinogenesis 18:1225-1231(1997)

Patent=US6255058
Webber M.M., Rhim J.S.
Immortalized and malignant human prostatic cell lines.
Patent number US6255058, 03-Jul-2001

PubMed=12725112; DOI=10.1385/1-59259-372-0:21
Russell P.J., Kingsley E.A.
Human prostate cancer cell lines.
Methods Mol. Med. 81:21-39(2003)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458
Rothenberg S.M., Mohapatra G., Rivera M.N., Winokur D., Greninger P., Nitta M., Sadow P.M., Sooriyakumar G., Brannigan B.W., Ulman M.J., Perera R.M., Wang R., Tam A., Ma X.-J., Erlander M., Sgroi D.C., Rocco J.W., Lingen M.W., Cohen E.E.W., Louis D.N., Settleman J., Haber D.A.
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-11610
CCTCC; GDC0179
KCB; KCB 2013044YJ
Cell line databases/resources CLO; CLO_0008906
cancercelllines; CVCL_3792
CCRID; 4201HUM-CCTCC00179
Cell_Model_Passport; SIDM01234
Lonza; 1673
Anatomy/cell type resources BTO; BTO:0005994
Biological sample resources ENCODE; ENCBS796LYI
ENCODE; ENCBS942OEI
Encyclopedic resources Wikidata; Q54951498
Experimental variables resources EFO; EFO_0007610
Gene expression databases GEO; GSM827388
Polymorphism and mutation databases Progenetix; CVCL_3792
Entry history
Entry creation04-Apr-2012
Last entry update05-Oct-2023
Version number28