Cellosaurus logo
expasy logo

Cellosaurus RWPE-2 (CVCL_3792)

[Text version]
Cell line name RWPE-2
Synonyms RWPE2
Accession CVCL_3792
Resource Identification Initiative To cite this cell line use: RWPE-2 (RRID:CVCL_3792)
Comments Group: Patented cell line.
Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11610.
Population: Caucasian.
Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P01117; Kirsten murine sarcoma virus k-Ras (v-Ki-ras).
Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
Omics: Variations; SNP array analysis.
Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
Cell type: Epithelial cell of prostate; CL=CL_0002231.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Parent: CVCL_3791 (RWPE-1)
Children:
CVCL_3793 (RWPE2-W99)
Sex of cell Male
Age at sampling 54Y
Category Transformed cell line
STR profile Source(s): ATCC=CRL-3608

Markers:
AmelogeninX,Y
CSF1PO13
D5S81812,15
D7S82010,11
D13S3178,14
D16S5399,11
TH018,9.3
TPOX8,11
vWA14,18

Run an STR similarity search on this cell line
Publications

PubMed=9018337; DOI=10.1002/(SICI)1097-0045(19970101)30:1<58::AID-PROS9>3.0.CO;2-H
Mukta M. Webber, Diana Bello, Salmaan T.A. Quader;
Immortalized and tumorigenic adult human prostatic epithelial cell lines: characteristics and applications Part 2. Tumorigenic cell lines.
Prostate 30:58-64(1997)

PubMed=9214605; DOI=10.1093/carcin/18.6.1215
Diana Bello, Mukta M. Webber, Hynda Karen Kleinman, David Don Wartinger, Johng Sik Rhim;
Androgen responsive adult human prostatic epithelial cell lines immortalized by human papillomavirus 18.
Carcinogenesis 18:1215-1223(1997)

PubMed=9214606; DOI=10.1093/carcin/18.6.1225
Mukta M. Webber, Diana Bello, Hynda Karen Kleinman, Matthew P. Hoffman;
Acinar differentiation by non-malignant immortalized human prostatic epithelial cells and its loss by malignant cells.
Carcinogenesis 18:1225-1231(1997)

Patent=US6255058
Mukta M. Webber, Johng Sik Rhim;
Immortalized and malignant human prostatic cell lines.
Patent number US6255058, 03-Jul-2001

PubMed=12725112; DOI=10.1385/1-59259-372-0:21
Pamela J. Russell, Elizabeth A. Kingsley;
Human prostate cancer cell lines.
Methods Mol. Med. 81:21-39(2003)

PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662
S. Michael Rothenberg, Gayatry Mohapatra, Miguel N. Rivera, Daniel Winokur, Patricia Greninger, Mai Nitta, Peter M. Sadow, Gaya Sooriyakumar, Brian W. Brannigan, Matthew J. Ulman, Rushika M. Perera ...Show all 22 authors... , Rui Wang, Angela Tam, Xiao-Jun Ma, Mark Erlander, Dennis C. Sgroi, James W. Rocco, Mark W. Lingen, Ezra E.W. Cohen, David Neil Louis, Jeffrey Settleman, Daniel Arie Haber; Show fewer authors
A genome-wide screen for microdeletions reveals disruption of polarity complex genes in diverse human cancers.
Cancer Res. 70:2158-2164(2010)

Cross-references
Cell line collections (Providers) ATCC; CRL-3608
ATCC; CRL-11610 - Discontinued
CCTCC; GDC0179
KCB; KCB 2013044YJ
Cell line databases/resources CLO; CLO_0008906
cancercelllines; CVCL_3792
CCRID; 4201HUM-CCTCC00179
Cell_Model_Passport; SIDM01234
Lonza; 1673
Anatomy/cell type resources BTO; BTO_0005994
Biological sample resources ENCODE; ENCBS796LYI
ENCODE; ENCBS942OEI
Encyclopedic resources Wikidata; Q54951498
Experimental variables resources EFO; EFO_0007610
Gene expression databases GEO; GSM827388
Polymorphism and mutation databases Progenetix; CVCL_3792
Entry history
Entry creation04-Apr-2012
Last entry update10-Apr-2025
Version number32