ID   RWPE-2
AC   CVCL_3792
SY   RWPE2
DR   BTO; BTO_0005994
DR   CLO; CLO_0008906
DR   EFO; EFO_0007610
DR   ATCC; CRL-3608
DR   ATCC; CRL-11610
DR   cancercelllines; CVCL_3792
DR   CCRID; 4201HUM-CCTCC00179
DR   CCTCC; GDC0179
DR   Cell_Model_Passport; SIDM01234
DR   ENCODE; ENCBS796LYI
DR   ENCODE; ENCBS942OEI
DR   GEO; GSM827388
DR   KCB; KCB 2013044YJ
DR   Lonza; 1673
DR   Progenetix; CVCL_3792
DR   Wikidata; Q54951498
RX   Patent=US6255058;
RX   PubMed=9018337;
RX   PubMed=9214605;
RX   PubMed=9214606;
RX   PubMed=12725112;
RX   PubMed=20215515;
CC   Group: Patented cell line.
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-11610.
CC   Population: Caucasian.
CC   Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P01117; Kirsten murine sarcoma virus k-Ras (v-Ki-ras).
CC   Transformant: NCBI_TaxID; 333761; Human papillomavirus type 18 (HPV18).
CC   Omics: Variations; SNP array analysis.
CC   Discontinued: ATCC; CRL-11610; true.
CC   Derived from site: In situ; Prostate, epithelium; UBERON=UBERON_0000428.
CC   Cell type: Epithelial cell of prostate; CL=CL_0002231.
ST   Source(s): ATCC=CRL-3608
ST   Amelogenin: X,Y
ST   CSF1PO: 13
ST   D13S317: 8,14
ST   D16S539: 9,11
ST   D5S818: 12,15
ST   D7S820: 10,11
ST   TH01: 8,9.3
ST   TPOX: 8,11
ST   vWA: 14,18
OX   NCBI_TaxID=9606; ! Homo sapiens (Human)
HI   CVCL_3791 ! RWPE-1
SX   Male
AG   54Y
CA   Transformed cell line
DT   Created: 04-04-12; Last updated: 10-04-25; Version: 32
CH   CVCL_3793 ! RWPE2-W99
//
RX   PubMed=9018337; DOI=10.1002/(SICI)1097-0045(19970101)30:1<58::AID-PROS9>3.0.CO;2-H;
RA   Webber, Mukta M.
RA   Bello, Diana
RA   Quader, Salmaan T.A.
RT   "Immortalized and tumorigenic adult human prostatic epithelial cell
RT   lines: characteristics and applications Part 2. Tumorigenic cell
RT   lines.";
RL   Prostate 30:58-64(1997).
//
RX   PubMed=12725112; DOI=10.1385/1-59259-372-0:21;
RA   Russell, Pamela Joan
RA   Kingsley, Elizabeth A.
RT   "Human prostate cancer cell lines.";
RL   Methods Mol. Med. 81:21-39(2003).
//
RX   Patent=US6255058;
RA   Webber, Mukta M.
RA   Rhim, Johng Sik
RT   "Immortalized and malignant human prostatic cell lines.";
RL   Patent number US6255058, 03-Jul-2001.
//
RX   PubMed=9214606; DOI=10.1093/carcin/18.6.1225;
RA   Webber, Mukta M.
RA   Bello, Diana
RA   Kleinman, Hynda Karen
RA   Hoffman, Matthew P.
RT   "Acinar differentiation by non-malignant immortalized human prostatic
RT   epithelial cells and its loss by malignant cells.";
RL   Carcinogenesis 18:1225-1231(1997).
//
RX   PubMed=20215515; DOI=10.1158/0008-5472.CAN-09-3458; PMCID=PMC2881662;
RA   Rothenberg, S. Michael
RA   Mohapatra, Gayatry
RA   Rivera, Miguel N.
RA   Winokur, Daniel
RA   Greninger, Patricia
RA   Nitta, Mai
RA   Sadow, Peter M.
RA   Sooriyakumar, Gaya
RA   Brannigan, Brian W.
RA   Ulman, Matthew J.
RA   Perera, Rushika M.
RA   Wang, Rui
RA   Tam, Angela
RA   Ma, Xiao-Jun
RA   Erlander, Mark
RA   Sgroi, Dennis C.
RA   Rocco, James W.
RA   Lingen, Mark W.
RA   Cohen, Ezra E.W.
RA   Louis, David Neil
RA   Settleman, Jeffrey
RA   Haber, Daniel Arie
RT   "A genome-wide screen for microdeletions reveals disruption of
RT   polarity complex genes in diverse human cancers.";
RL   Cancer Res. 70:2158-2164(2010).
//
RX   PubMed=9214605; DOI=10.1093/carcin/18.6.1215;
RA   Bello, Diana
RA   Webber, Mukta M.
RA   Kleinman, Hynda Karen
RA   Wartinger, David Don
RA   Rhim, Johng Sik
RT   "Androgen responsive adult human prostatic epithelial cell lines
RT   immortalized by human papillomavirus 18.";
RL   Carcinogenesis 18:1215-1223(1997).
//