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Cellosaurus DDT1-MF2 (CVCL_3459)

[Text version]
Cell line name DDT1-MF2
Synonyms DDT-1 MF-2; DDT1 MF-2; DDT1-MF-2; DDT1 MF2; DDT1MF-2; DDT1MF2; DDT1 clone MF-2; DDT-WT
Accession CVCL_3459
Resource Identification Initiative To cite this cell line use: DDT1-MF2 (RRID:CVCL_3459)
Comments Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12051.
Transformant: ChEBI; CHEBI_41922; Diethylstilbestrol.
Derived from site: In situ; Vas deferens, smooth muscle; UBERON=UBERON_0004224.
Disease Hamster ductus deferens leiomyosarcoma (NCIt: C134567)
Species of origin Mesocricetus auratus (Golden hamster) (NCBI Taxonomy: 10036)
Hierarchy Parent: CVCL_DC05 (DDT1)
Children:
CVCL_DC06 (DDT/TG500nM)CVCL_C7S1 (DDT1-MF2 GR1)
Sex of cell Male
Category Cancer cell line
Publications

PubMed=179138; DOI=10.1126/science.179138
James S. Norris, Peter O. Kohler;
Characterization of the androgen receptor from a Syrian hamster ductus deferens tumor cell line (DDT1).
Science 192:898-900(1976)

PubMed=6662552; DOI=10.1007/BF02661714
Allan J. Syms, James S. Norris, Roy G. Smith;
Proliferation of a highly androgen-sensitive ductus deferens cell line (DDT1MF-2) is regulated by glucocorticoids and modulated by growth on collagen.
In Vitro 19:929-936(1983)

PubMed=6708513; DOI=10.1016/0022-4731(84)90217-6
Roy G. Smith, Allan J. Syms, James S. Norris;
Differential effects of androgens and glucocorticoids on regulation of androgen receptor concentrations and cell growth.
J. Steroid Biochem. 20:277-281(1984)

PubMed=4058427; DOI=10.1007/BF00219391
James S. Norris, Lawrence E. Cornett, Peter O. Kohler, Stewart L. MacLeod, Allan J. Syms, Roy G. Smith;
Glucocorticoids induce a 29 000 Mr protein in DDT1 MF-2 smooth muscle cells but not in the DDT1 MF-2 GR glucocorticoid resistant variant.
Mol. Cell. Biochem. 68:79-85(1985)

PubMed=1314696
William J. Hendry 3rd, Reza Hakkak, Lawrence E. Cornett;
Selective loss of glucocorticoid-dependent responses in a variant of the DDT1MF-2 tumor cell line.
Cancer Res. 52:2516-2522(1992)

PubMed=8314862; DOI=10.1002/jcp.1041560113
Wei-Min Fan, Tina M. Cooper, James S. Norris;
Characterization of selective glucocorticoid-dependent responses in a glucocorticoid-resistant smooth muscle tumor cell line.
J. Cell. Physiol. 156:88-95(1993)

Cross-references
Cell line collections (Providers) ATCC; CRL-1701
BCRC; 60498
ECACC; 89051703
Cell line databases/resources CLO; CLO_0002734
CLO; CLO_0002735
CLO; CLO_0002736
CLDB; cl1014
Anatomy/cell type resources BTO; BTO_0002594
Encyclopedic resources Wikidata; Q54830941
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number14