ID   DDT1-MF2
AC   CVCL_3459
SY   DDT-1 MF-2; DDT1 MF-2; DDT1-MF-2; DDT1 MF2; DDT1MF-2; DDT1MF2; DDT1 clone MF-2; DDT-WT
DR   BTO; BTO_0002594
DR   CLO; CLO_0002734
DR   CLO; CLO_0002735
DR   CLO; CLO_0002736
DR   CLDB; cl1014
DR   ATCC; CRL-1701
DR   ATCC; CRL-12051
DR   BCRC; 60498
DR   ECACC; 89051703
DR   Wikidata; Q54830941
RX   PubMed=179138;
RX   PubMed=1314696;
RX   PubMed=4058427;
RX   PubMed=6662552;
RX   PubMed=6708513;
RX   PubMed=8314862;
CC   Registration: International Depositary Authority, American Type Culture Collection (ATCC); CRL-12051.
CC   Transformant: ChEBI; CHEBI_41922; Diethylstilbestrol.
CC   Derived from site: In situ; Vas deferens, smooth muscle; UBERON=UBERON_0004224.
DI   NCIt; C134567; Hamster ductus deferens leiomyosarcoma
OX   NCBI_TaxID=10036; ! Mesocricetus auratus (Golden hamster)
HI   CVCL_DC05 ! DDT1
SX   Male
CA   Cancer cell line
DT   Created: 04-04-12; Last updated: 19-12-24; Version: 13
//
RX   PubMed=179138; DOI=10.1126/science.179138;
RA   Norris J.S., Kohler P.O.;
RT   "Characterization of the androgen receptor from a Syrian hamster
RT   ductus deferens tumor cell line (DDT1).";
RL   Science 192:898-900(1976).
//
RX   PubMed=1314696;
RA   Hendry W.J. 3rd, Hakkak R., Cornett L.E.;
RT   "Selective loss of glucocorticoid-dependent responses in a variant of
RT   the DDT1MF-2 tumor cell line.";
RL   Cancer Res. 52:2516-2522(1992).
//
RX   PubMed=4058427; DOI=10.1007/BF00219391;
RA   Norris J.S., Cornett L.E., Kohler P.O., MacLeod S.L., Syms A.J.,
RA   Smith R.G.;
RT   "Glucocorticoids induce a 29 000 Mr protein in DDT1 MF-2 smooth muscle
RT   cells but not in the DDT1 MF-2 GR glucocorticoid resistant variant.";
RL   Mol. Cell. Biochem. 68:79-85(1985).
//
RX   PubMed=6662552; DOI=10.1007/BF02661714;
RA   Syms A.J., Norris J.S., Smith R.G.;
RT   "Proliferation of a highly androgen-sensitive ductus deferens cell
RT   line (DDT1MF-2) is regulated by glucocorticoids and modulated by
RT   growth on collagen.";
RL   In Vitro 19:929-936(1983).
//
RX   PubMed=6708513; DOI=10.1016/0022-4731(84)90217-6;
RA   Smith R.G., Syms A.J., Norris J.S.;
RT   "Differential effects of androgens and glucocorticoids on regulation
RT   of androgen receptor concentrations and cell growth.";
RL   J. Steroid Biochem. 20:277-281(1984).
//
RX   PubMed=8314862; DOI=10.1002/jcp.1041560113;
RA   Fan W.-M., Cooper T.M., Norris J.S.;
RT   "Characterization of selective glucocorticoid-dependent responses in a
RT   glucocorticoid-resistant smooth muscle tumor cell line.";
RL   J. Cell. Physiol. 156:88-95(1993).
//