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Cellosaurus Lec8 (CVCL_3443)

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Cell line name Lec8
Synonyms CHO-Lec8; CHO Lec8; Pro-Lec8.D3; Pro-5WgaRVIII3D
Accession CVCL_3443
Resource Identification Initiative To cite this cell line use: Lec8 (RRID:CVCL_3443)
Comments Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations
  • Mutation; UniProtKB; Q99PG7; Slc35a2; Simple; p.Gly92Ter (c.275_374del); Zygosity=Unspecified (from parent cell line).
Species of origin Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy Parent: CVCL_4382 (CHO Pro-5)
Children:
CVCL_D2U2 (Lec8/hPDPN)CVCL_D2TT (Lec8/PODXL)CVCL_B7JW (Lec8/TROP2)
Sex of cell Female
Age at sampling Adult
Category Spontaneously immortalized cell line
Publications

PubMed=9279382; DOI=10.1128/mcb.1.8.687-696.1981; PMCID=PMC369349
Pamela Stanley;
Selection of specific wheat germ agglutinin-resistant (WgaR) phenotypes from Chinese hamster ovary cell populations containing numerous lecR genotypes.
Mol. Cell. Biol. 1:687-696(1981)

PubMed=3785164; DOI=10.1128/mcb.6.4.1268-1275.1986; PMCID=PMC367639
James Ripka, Seung-Il Shin, Pamela Stanley;
Decreased tumorigenicity correlates with expression of altered cell surface carbohydrates in Lec9 CHO cells.
Mol. Cell. Biol. 6:1268-1275(1986)

PubMed=11319223; DOI=10.1074/jbc.M011124200
Stefan Oelmann, Pamela Stanley, Rita Gerardy-Schahn;
Point mutations identified in Lec8 Chinese hamster ovary glycosylation mutants that inactivate both the UDP-galactose and CMP-sialic acid transporters.
J. Biol. Chem. 276:26291-26300(2001)

Cross-references
Cell line collections (Providers) ATCC; CRL-1737
Cell line databases/resources CLO; CLO_0007303
Anatomy/cell type resources BTO; BTO_0006507
Encyclopedic resources Wikidata; Q54902427
Entry history
Entry creation04-Apr-2012
Last entry update19-Dec-2024
Version number13