Cellosaurus cell line Lec8/hPDPN (CVCL

Cellosaurus Lec8/hPDPN (CVCL_D2U2)

Cross-references
Cell line name	Lec8/hPDPN
Accession	CVCL_D2U2
Resource Identification Initiative	To cite this cell line use: Lec8/hPDPN (RRID:CVCL_D2U2)
Comments	Genetic integration: Method=Transfection/transduction; Gene=HGNC; HGNC:29602; PDPN. Genetic integration: Method=Transfection/transduction; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo. Derived from site: In situ; Ovary; UBERON=UBERON_0000992. Cell type: Epithelial cell of ovary; CL=CL_2000064.
Sequence variations	Mutation; UniProtKB; Q99PG7; Slc35a2; Simple; p.Gly92Ter (c.275_374del); Zygosity=Unspecified (from parent cell line).
Species of origin	Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) (NCBI Taxonomy: 10029)
Hierarchy	Parent: CVCL_3443 (Lec8)
Sex of cell	Female
Age at sampling	Adult
Category	Spontaneously immortalized cell line
Publications	PubMed=25080943; DOI=10.1038/srep05924; PMCID=PMC4118152 Yukinari Kato, Mika Kato Kaneko; A cancer-specific monoclonal antibody recognizes the aberrantly glycosylated podoplanin. Sci. Rep. 4:5924.1-5924.9(2014) PubMed=26937552; DOI=10.1089/mab.2015.0077 Yukinari Kato, Satoshi Ogasawara, Hiroharu Oki, Ryusuke Honma, Michiaki Takagi, Yuki Fujii, Takuro Nakamura, Noriko Saidoh, Hazuki Kanno, Mitsuo Umetsu, Satoshi Kamata ...Show all 18 authors... , Hiroshi Kubo, Mitsuhiro Yamada, Yoshihiko Sawa, Kei-ichi Morita, Hiroyuki Harada, Hiroyoshi Suzuki, Mika Kato Kaneko; Show fewer authors Novel monoclonal antibody LpMab-17 developed by CasMab technology distinguishes human podoplanin from monkey podoplanin. Monoclon. Antib. Immunodiagn. Immunother. 35:109-116(2016) PubMed=27328060; DOI=10.1089/mab.2016.0006 Satoshi Ogasawara, Mika Kato Kaneko, Ryusuke Honma, Hiroharu Oki, Yuki Fujii, Michiaki Takagi, Hiroyoshi Suzuki, Yukinari Kato; Establishment of mouse monoclonal antibody LpMab-13 against human podoplanin. Monoclon. Antib. Immunodiagn. Immunother. 35:155-162(2016) Patent=US10227407 Yukinari Kato, Mika Kato Kaneko; Anti-podoplanin antibody. Patent number US10227407, 12-Mar-2019
Encyclopedic resources	Wikidata; Q127382590
Entry history
Entry creation	30-Jan-2024
Last entry update	14-Aug-2025
Version number	4