ID   Lec8
AC   CVCL_3443
SY   CHO-Lec8; CHO Lec8; Pro-Lec8.D3; Pro-5WgaRVIII3D
DR   BTO; BTO:0006507
DR   CLO; CLO_0007303
DR   ATCC; CRL-1737
DR   Wikidata; Q54902427
RX   PubMed=3785164;
RX   PubMed=9279382;
RX   PubMed=11319223;
CC   Sequence variation: Mutation; UniProtKB; Q99PG7; Slc35a2; Simple; p.Gly92Ter (c.275_374del); Zygosity=Unspecified (from parent cell line).
CC   Derived from site: In situ; Ovary; UBERON=UBERON_0000992.
CC   Cell type: Epithelial cell of ovary; CL=CL_2000064.
OX   NCBI_TaxID=10029; ! Cricetulus griseus (Chinese hamster)
HI   CVCL_4382 ! CHO Pro-5
SX   Female
AG   Adult
CA   Spontaneously immortalized cell line
DT   Created: 04-04-12; Last updated: 30-01-24; Version: 12
//
RX   PubMed=3785164; DOI=10.1128/mcb.6.4.1268-1275.1986;
RA   Ripka J., Shin S.-I., Stanley P.;
RT   "Decreased tumorigenicity correlates with expression of altered cell
RT   surface carbohydrates in Lec9 CHO cells.";
RL   Mol. Cell. Biol. 6:1268-1275(1986).
//
RX   PubMed=9279382; DOI=10.1128/mcb.1.8.687-696.1981;
RA   Stanley P.;
RT   "Selection of specific wheat germ agglutinin-resistant (WgaR)
RT   phenotypes from Chinese hamster ovary cell populations containing
RT   numerous lecR genotypes.";
RL   Mol. Cell. Biol. 1:687-696(1981).
//
RX   PubMed=11319223; DOI=10.1074/jbc.M011124200;
RA   Oelmann S., Stanley P., Gerardy-Schahn R.;
RT   "Point mutations identified in Lec8 Chinese hamster ovary
RT   glycosylation mutants that inactivate both the UDP-galactose and
RT   CMP-sialic acid transporters.";
RL   J. Biol. Chem. 276:26291-26300(2001).
//