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Cellosaurus PHK16-0b (CVCL_3123)

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Cell line name PHK16-0b
Synonyms PHK160b
Accession CVCL_3123
Resource Identification Initiative To cite this cell line use: PHK16-0b (RRID:CVCL_3123)
Comments Population: Caucasian.
Characteristics: Transfected with the plasmid pMHPV16d, which contains two copies of the complete HPV16 genome in a head-to-tail configuration (PubMed=1848315).
Genetic integration: Method=Transfection; Gene=UniProtKB; P00552; Klebsiella pneumoniae transposon Tn5 neo.
Transformant: NCBI_TaxID; 333760; Human papillomavirus type 16 (HPV16).
Derived from site: In situ; Skin, epidermis; UBERON=UBERON_0001003.
Cell type: Keratinocyte; CL=CL_0000312.
Species of origin Homo sapiens (Human) (NCBI Taxonomy: 9606)
Hierarchy Children:
CVCL_U219 (NCC16)
Sex of cell Male
Age at sampling Age unspecified
Category Transformed cell line
STR profile Source(s): JCRB=JCRB0141

Markers:
AmelogeninX,Y
CSF1PO12,13
D5S8189,11
D7S8209,11
D13S31711
D16S53911,12
TH019.3
TPOX8
vWA16

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Publications

PubMed=2173586; DOI=10.1016/0006-291x(90)90769-j
Takashi Hashida, Shigeru Yasumoto;
Casein kinase II activities related to hyperphosphorylation of human papillomavirus type 16-E7 oncoprotein in epidermal keratinocytes.
Biochem. Biophys. Res. Commun. 172:958-964(1990)

PubMed=1848315; DOI=10.1128/JVI.65.4.2000-2009.1991; PMCID=PMC240041
Shigeru Yasumoto, Akiyoshi Taniguchi, Kazunori Sohma;
Epidermal growth factor (EGF) elicits down-regulation of human papillomavirus type 16 (HPV-16) E6/E7 mRNA at the transcriptional level in an EGF-stimulated human keratinocyte cell line: functional role of EGF-responsive silencer in the HPV-16 long control region.
J. Virol. 65:2000-2009(1991)

Cross-references
Cell line collections (Providers) JCRB; JCRB0141
JCRB; NIHS0203 - Discontinued
Biological sample resources BioSample; SAMN03470808
Encyclopedic resources Wikidata; Q54947361
Entry history
Entry creation04-Apr-2012
Last entry update14-Aug-2025
Version number16